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DKK3 Protein (AA 1-349) (His tag)

Origine: Souris Hôte: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7505749
  • Antigène Tous les produits DKK3
    DKK3
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1-349
    Origine
    • 11
    • 3
    • 1
    • 1
    Souris
    Source
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette DKK3 protéine est marqué à la His tag.
    Séquence
    Met1-Ile349
    Attributs du produit
    A DNA sequence encoding the Mouse DKK3 protein (Q9QUN9) (Met1-Ile349) was expressed with a C-His.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Date de péremption
    12 months
  • Antigène
    DKK3
    Abstract
    DKK3 Produits
    Synonymes
    REIC Protein, RIG Protein, reic Protein, dkk-3 Protein, AW061014 Protein, C87148 Protein, Reic Protein, p29 Protein, dickkopf WNT signaling pathway inhibitor 3 Protein, dickkopf WNT signaling pathway inhibitor 3 S homeolog Protein, DKK3 Protein, dkk3 Protein, dkk3.S Protein, Dkk3 Protein
    Sujet

    Abbreviation: DKK3

    Target Synonym: AW061014,C87148

    Background: DKK3 (dickkopf related protein 3) is a member of the dickkopf-related family consisting of DKK1, DKK2, DKK3 and DKK4. It is a secreted protein, and also known as REIC (Reduced Expansion in Immortalized Cells). The DKK3 protein is proposed to function as a secreted tumor suppressor since it is downregulated in a number of cancer cells and prostate cancer tissue and may be a promising candidate molecule for therapeutic interference. DKK3 protein is also a negative regulator of beta-catenin and its downregulation contribute to an activation of the beta-catenin signaling pathway.

    Poids moléculaire

    Calculated MW: 38.28 kDa

    Observed MW: 60 kDa

    UniProt
    Q9QUN9
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