Tissue factor Protein (AA 1-252) (His tag)
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- Antigène Voir toutes Tissue factor (F3) Protéines
- Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-252
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Origine
- Rat
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette Tissue factor protéine est marqué à la His tag.
- Séquence
- Met1-Glu252
- Attributs du produit
- A DNA sequence encoding the Rat TF protein (P42533) (Met1-Glu252) was expressed with a C-His.
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product F3 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Date de péremption
- 12 months
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- Antigène
- Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))
- Autre désignation
- Tissue factor (F3 Produits)
- Synonymes
- CD142 Protein, TF Protein, TFA Protein, PRO1557 Protein, PRO2086 Protein, TFQTL1 Protein, f3 Protein, AA409063 Protein, Cf-3 Protein, Cf3 Protein, tf Protein, zgc:112151 Protein, coagulation factor III, tissue factor Protein, transferrin Protein, coagulation factor IIIa Protein, coagulation factor III Protein, tissue factor Protein, coagulation factor IIIb Protein, coagulation factor III (thromboplastin, tissue factor) S homeolog Protein, F3 Protein, TF Protein, f3a Protein, tf Protein, f3b Protein, f3.S Protein
- Sujet
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Abbreviation: Tissue factor,TF
Target Synonym: Tissue factor,TF,Coagulation factor III,CD antigen CD142,F3,Cf3
Background: Coagulation Factor III/Tissue Factor (TF), also known as thromboplastin and CD142, is an integral membrane protein found in a variety of cell types. It functions as a protein cofactor/receptor of Coagulation Factor VII, which is synthesized in the liver and circulated in the plasma. Upon binding of TF, the inactive factor VII is rapidly converted into activated VIIa. The resulting 1:1 complex of VIIa and TF initiates the coagulation pathway and has also important coagulation-independent functions such as angiognesis. Synthesized as a 294 amino acid precursor, mouse TF consists of a signal peptide (residues 1 to 28) and the mature chain (residues 29 to 294). As a type I membrane protein, it contains a transmembrane region (residues 252 to 274) and a cytoplasmic tail (residues 275 to 294).
- Poids moléculaire
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Calculated MW: 27.61 kDa
Observed MW: 49 kDa
- UniProt
- P42533
- Pathways
- Positive Regulation of Endopeptidase Activity, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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