Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

Bcl-2 Protéine

BCL2 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % by SDS-PAGE.
N° du produit ABIN7533828
  • Antigène Voir toutes Bcl-2 (BCL2) Protéines
    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
    Type de proteíne
    Recombinant
    Origine
    • 11
    • 4
    • 2
    • 2
    • 2
    Humain
    Source
    • 15
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Fonction
    Active Recombinant Human Bcl-2 Protein
    Séquence
    AHAGRTGYDN REIVMKYIHY KLSQRGYEWD AGDVGAAPPG AAPAPGIFSS QPGHTPHPAA SRDPVARTSP LQTPAAPGAA AGPALSPVPP VVHLTLRQAG DDFSRRYRRD FAEMSSQLHL TPFTARGRFA TVVEELFRDG VNWGRIVAFF EFGGVMCVES VNREMSPLVD NIALWMTEYL NRHLHTWIQD NGGWDAFVEL YGPSMRPLFD
    Specificité
    Ala2-Asp211
    Pureté
    > 90 % by SDS-PAGE.
    Stérilité
    0.22 μm filtered
    niveau d'endotoxine
    < 1.0 EU/μg of the protein by LAL method.
    Top Product
    Discover our top product BCL2 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    Buffer
    Lyophilized from a 0.22 μm filtered solution of 20 mM HEPES,50 mM KCl, pH 7.5.
    Stock
    -80 °C
    Stockage commentaire
    This product is stable at ≤ -70° C for up to 1 year from the date of receipt.
    For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature.
  • Antigène
    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
    Autre désignation
    Bcl-2 (BCL2 Produits)
    Synonymes
    Bcl-2 Protein, PPP1R50 Protein, bcl-2 Protein, AW986256 Protein, C430015F12Rik Protein, D630044D05Rik Protein, D830018M01Rik Protein, BCL-2 Protein, Bcl2 Protein, BCL2, apoptosis regulator Protein, B cell leukemia/lymphoma 2 Protein, B-cell CLL/lymphoma 2a Protein, B-cell CLL/lymphoma 2 protein Protein, BCL2 Protein, Bcl2 Protein, bcl2a Protein, BCL-2 Protein
    Sujet

    Description: This protein is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma.

    Name: BCL2, Bcl-2, PPP1R50, apoptosis regulator Bcl-2,Bcl-2,PPP1R50

    ID gène
    596
    UniProt
    P10415
    Pathways
    Signalisation MAPK, Signalisation PI3K-Akt, Apoptose, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
Vous êtes ici:
Support technique