CXCL3 Protéine

N° du produit ABIN7535397

Détail du produit

Antigène: CXCL3 (Chemokine (C-X-C Motif) Ligand 3 (CXCL3))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Fonction: Recombinant Human CXCL3/GRO-gamma/MIP2-beta Protein

Séquence: ASVVTELRCQ CLQTLQGIHL KNIQSVNVRS PGPHCAQTEV IATLKNGKKA CLNPASPMVQ KIIEKILNKG STN

Specificité: Ala35-Asn107

Pureté: > 85 % by SDS-PAGE.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: <1EU/μg

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Stock: -20 °C,-80 °C

Stockage commentaire: Store the lyophilized protein at -20°C to -80°C for long term.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

Détail du antigène

Antigène: CXCL3 (Chemokine (C-X-C Motif) Ligand 3 (CXCL3))

Autre désignation: CXCL3/GRO-gamma/MIP2-beta (CXCL3 Produits)

Synonymes: CXCL3 Protein, CINC-2b Protein, GRO3 Protein, GROg Protein, MIP-2b Protein, MIP2B Protein, SCYB3 Protein, Cinc-2 Protein, Cinc2 Protein, Gm1960 Protein, Dcip1 Protein, C-X-C motif chemokine ligand 3 Protein, chemokine (C-X-C motif) ligand 3 Protein, CXCL3 Protein, Cxcl3 Protein

Sujet:

Description: CXCL3 is involved in migration, invasion, proliferation and tubule formation of trophoblasts and may play a key role in the pathogenesis of preeclampsia. CXCL3 autocrine/paracrine pathways are involved in the development of prostate cancer by regulating the expression of the target genes that are related to the progression of malignancies. CXCL3 is a novel adipokine that facilitates adipogenesis in an autocrine and/or a paracrine manner through induction of c/ebpb and c/ebpd. CXCL3 and its receptor CXCR2 are overexpressed in prostate cancer cells, prostate epithelial cells and prostate cancer tissues, which may play multiple roles in prostate cancer progression and metastasis.

Name: CXCL3,CINC-2b,GRO3,GROg,MIP-2b,MIP2B,SCYB3

ID gène: 2921

UniProt: P19876

Pathways: Cellular Response to Molecule of Bacterial Origin, Autophagy