C3 Protein (His tag,AVI tag)

N° du produit ABIN7535473

Détail du produit

Antigène: C3 (Complement Component 3 (C3))

Type de proteíne: Recombinant

Origine: Souris

Source: HEK-293 Cells

Purification/Conjugué: Cette C3 protéine est marqué à la His tag,AVI tag.

Fonction: Recombinant Mouse Complement C3 Protein

Séquence: SVQLMERRMD KAGQYTDKGL RKCCEDGMRD IPMRYSCQRR ARLITQGENC IKAFIDCCNH ITKLREQHRR DHVLGLAR

Specificité: Ser671-Arg748

Pureté: > 95 % by SDS-PAGE.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: < 0.1 EU/μg of the protein by LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Stock: -20 °C,-80 °C

Stockage commentaire: Store the lyophilized protein at -20°C to -80°C for long term.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

Détail du antigène

Antigène: C3 (Complement Component 3 (C3))

Autre désignation: Complement C3 (C3 Produits)

Synonymes: AHUS5 Protein, ARMD9 Protein, ASP Protein, C3a Protein, C3b Protein, CPAMD1 Protein, AI255234 Protein, HSE-MSF Protein, Plp Protein, C3 Protein, C3-1 Protein, sb:cb26 Protein, si:dkey-76b14.4 Protein, wu:fi34b03 Protein, wu:fj86e11 Protein, C3d Protein, asp Protein, cpamd1 Protein, c3 Protein, complement C3 Protein, complement component 3 Protein, complement component c3a, duplicate 1 Protein, complement component 3 L homeolog Protein, complement component C3 Protein, complement C3-like Protein, C3 Protein, c3a.1 Protein, c3.L Protein, LOC443475 Protein, c3 Protein, c3-1 Protein, LOC100060539 Protein

Sujet:

Description: C3 is the major complement component serum. It is mainly synthesized by macrophages and liver. C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. It is cleaved into two fragments, C3a and C3b. C3a anaphylatoxin is a mediator of local inflammatory process. In chronic inflammation, acts as a chemoattractant for neutrophils. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.

Name: C3,AHUS5,ARMD9,ASP,C3a,C3b,CPAMD1,HEL-S-62p,complement C3,C3 / C3a

ID gène: 12266

UniProt: P01027-1

Pathways: Système du Complément, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling