FGFR1 Protein (Fc Tag,His tag)

N° du produit ABIN7534826

Détail du produit

Antigène: FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette FGFR1 protéine est marqué à la Fc Tag,His tag.

Fonction: Active Recombinant Human FLT-2/FGFR-1/CD331 Protein

Séquence: RPSPTLPEQA QPWGAPVEVE SFLVHPGDLL QLRCRLRDDV QSINWLRDGV QLAESNRTRI TGEEVEVQDS VPADSGLYAC VTSSPSGSDT TYFSVNVSDA LPSSEDDDDD DDSSSEEKET DNTKPNRMPV APYWTSPEKM EKKLHAVPAA KTVKFKCPSS GTPNPTLRWL KNGKEFKPDH RIGGYKVRYA TWSIIMDSVV PSDKGNYTCI VENEYGSINH TYQLDVVERS PHRPILQAGL PANKTVALGS NVEFMCKVYS DPQPHIQWLK HIEVNGSKIG PDNLPYVQIL KTAGVNTTDK EMEVLHLRNV SFEDAGEYTC LAGNSIGLSH HSAWLTVLEA LEERPAVMTS PLYLE

Specificité: Arg22-Glu376

Pureté: > 95 % by SDS-PAGE.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: < 0.1 EU/μg of the protein by LAL method.

Biological Activity Comment: 1.Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human FGF1 at 10 μg/mL (100 μL/well) can bind Recombinant Human FGFR1 with a linear range of 1.1-3.4 μg/mL.|2.Measured by its ability to inhibit FGF-acidic dependent proliferation of Balb/c 3T3 mouse fibroblasts. The ED₅₀ for this effect is typically 0.605-2.42 ng/mL.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Stock: -20 °C,-80 °C

Stockage commentaire: Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.

Détail du antigène

Antigène: FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))

Autre désignation: FLT-2/FGFR-1/CD331 (FGFR1 Produits)

Synonymes: FGFR Protein, fgfr Protein, X1FGFR Protein, XFGFR-1 Protein, XFGFRA2 Protein, bfgfr Protein, cek Protein, fgfr1 Protein, flg Protein, flt-2 Protein, flt2 Protein, kal2 Protein, ogd Protein, xfgfr1 Protein, CG7223 Protein, CT22273 Protein, CT39172 Protein, DFGF-R1 Protein, DFGF-R2 Protein, DFR-1 Protein, DFR1 Protein, DFR1/DFGF-R2 Protein, DPR3 Protein, DTRK(FR1) Protein, Dfr-1 Protein, Dfr1 Protein, DmHD-38 Protein, Dmel\\CG7223 Protein, Dtk1 Protein, EMS2 Protein, FGF-R2 Protein, FGFR2 Protein, FR1 Protein, Fr1 Protein, HD-38 Protein, HTL/FGFR1 Protein, Htl Protein, Tk1 Protein, dtk1 Protein, i100 Protein, i150 Protein, i79 Protein, j372 Protein, cd331 Protein, fgfbr Protein, fgfr-1 Protein, hbgfr Protein, n-sam Protein, ach Protein, cd333 Protein, cek2 Protein, fgfr-3 Protein, hsfgfr3ex Protein, jtk4 Protein, BFGFR Protein, CD331 Protein, CEK Protein, FGFBR Protein, FGFR-1 Protein, FLG Protein, FLT-2 Protein, FLT2 Protein, HBGFR Protein, HH2 Protein, KAL2 Protein, N-SAM Protein, OGD Protein, bFGF-R-1 Protein, AW208770 Protein, Eask Protein, Fgfr-1 Protein, Flt-2 Protein, Hspy Protein, FLG-1 Protein, FGFRI Protein, x1fgfr Protein, cb231 Protein, sb:cb231 Protein, fibroblast growth factor receptor Protein, fibroblast growth factor receptor 1 S homeolog Protein, basic fibroblast growth factor receptor 1 Protein, heartless Protein, fibroblast growth factor receptor 1 Protein, fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) L homeolog Protein, Fibroblast growth factor receptor 1 Protein, fibroblast growth factor receptor 1 L homeolog Protein, fibroblast growth factor receptor 1a Protein, FGFR Protein, fgfr Protein, fgfr1.S Protein, CpipJ_CPIJ005849 Protein, htl Protein, fgfr1 Protein, fgfr3.L Protein, FGFR1 Protein, Fgfr1 Protein, fgfr1.L Protein, fgfr1a Protein

Sujet: FGFR1,BFGFR,CD331,CEK,ECCL,FGFBR,FGFR-1,FLG,FLT-2,FLT2,HBGFR,HH2,HRTFDS,KAL2,N-SAM,OGD,bFGF-R-1

ID gène: 2260

UniProt: P11362-1

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, S100 Proteins