IL1RL2 Protein (His tag)

N° du produit ABIN7520130

Détail du produit

Antigène: IL1RL2 (Interleukin 1 Receptor-Like 2 (IL1RL2))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette IL1RL2 protéine est marqué à la His tag.

Fonction: Recombinant Human IL-36R/IL-1Rrp2/IL1RL2 Protein

Séquence: DGCKDIFMKN EILSASQPFA FNCTFPPITS GEVSVTWYKN SSKIPVSKII QSRIHQDETW ILFLPMEWGD SGVYQCVIKG RDSCHRIHVN LTVFEKHWCD TSIGGLPNLS DEYKQILHLG KDDSLTCHLH FPKSCVLGPI KWYKDCNEIK GERFTVLETR LLVSNVSAED RGNYACQAIL THSGKQYEVL NGITVSITER AGYGGSVPKI IYPKNHSIEV QLGTTLIVDC NVTDTKDNTN LRCWRVNNTL VDDYYDESKR IREGVETHVS FREHNLYTVN ITFLEVKMED YGLPFMCHAG VSTAYIILQL PAPDFR

Specificité: Asp20-Arg335

Pureté: > 95 % by SDS-PAGE.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: <0.1EU/μg

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Stock: -20 °C,-80 °C

Stockage commentaire: Store the lyophilized protein at -20°C to -80°C for long term.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

Détail du antigène

Antigène: IL1RL2 (Interleukin 1 Receptor-Like 2 (IL1RL2))

Autre désignation: IL-36R/IL-1Rrp2/IL1RL2 (IL1RL2 Produits)

Synonymes: IL-1Rrp2 Protein, IL-36R Protein, IL1R-rp2 Protein, IL1RRP2 Protein, AI481289 Protein, AW551444 Protein, interleukin 1 receptor like 2 Protein, interleukin 1 receptor-like 2 Protein, IL1RL2 Protein, Il1rl2 Protein

Sujet:

Description: IL1RL2 (Interleukin 1 Receptor-Like 2, also known as IL-36R) is a Protein Coding gene. The protein encoded by this gene is a member of the interleukin 1 receptor family. This gene and four other interleukin 1 receptor family genes form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. The IL36 receptor is an important mediator molecule in the inflammatory response. Animal data suggest that IL1RL2 is involved in mucosal healing. Therapeutic intervention of IL-36R signaling offers an innovative treatment paradigm for targeting epithelial cell-mediated inflammatory diseases such as the life-threatening psoriasis variant called generalized pustular psoriasis (GPP). Diseases associated with IL1RL2 include Familial Cold Autoinflammatory Syndrome 2 and Geographic Tongue.

Name: IL1RL2,IL-1Rrp2,IL-36R,IL1R-rp2,IL1RRP2,IL36R

ID gène: 8808

UniProt: Q9HB29