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IL21 Receptor Protein (His tag)

IL21R Origine: Souris Hôte: HEK-293 Cells Recombinant > 97 % by SDS-PAGE. Active
N° du produit ABIN7534805
  • Antigène Voir toutes IL21 Receptor (IL21R) Protéines
    IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Origine
    • 12
    • 4
    • 2
    • 1
    Souris
    Source
    • 12
    • 3
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette IL21 Receptor protéine est marqué à la His tag.
    Fonction
    Active Recombinant Mouse IL-21R/CD360 Protein
    Séquence
    CLDLTCYTDY LWTITCVLET RSPNPSILSL TWQDEYEELQ DQETFCSLHR SGHNTTHIWY TCHMRLSQFL SDEVFIVNVT DQSGNNSQEC GSFVLAESIK PAPPLNVTVA FSGRYDISWD SAYDEPSNYV LRGKLQYELQ YRNLRDPYAV RPVTKLISVD SRNVSLLPEE FHKDSSYQLQ VRAAPQPGTS FRGTWSEWSD PVIFQTQAGE PEAGWDP
    Specificité
    Cys20-Pro236
    Pureté
    > 97 % by SDS-PAGE.
    Stérilité
    0.22 μm filtered
    niveau d'endotoxine
    < 0.1 EU/μg of the protein by LAL method.
    Biological Activity Comment
    Measured by its binding ability in a functional ELISA. Immobilized Recombinant Mouse IL21R at 2 μg/mL (100 μL/well) can bind Recombinant Human IL-21 with a linear range of 0.128-83.57 ng/mL.
    Top Product
    Discover our top product IL21R Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    Buffer
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • Antigène
    IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))
    Autre désignation
    IL-21R/CD360 (IL21R Produits)
    Synonymes
    IL21R Protein, il-21ra.a Protein, CD360 Protein, NILR Protein, interleukin 21 receptor Protein, interleukin 21 receptor, tandem duplicate 1 Protein, IL21R Protein, il21r.1 Protein, Il21r Protein
    Sujet

    Description: Interleukin-21 receptor, also known as IL-21 receptor, IL-21R, Novel interleukin receptor, IL21R and NILR, is a single-pass type I membrane protein which belongs to the type I cytokine receptor family and Type 4 subfamily. Interleukin-21 (IL-21) belongs to a family of cytokines,and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3.

    Name: CD360,NILR,IL-21 R,IL-21 receptor,IL21R,IL-21R,interleukin 21 receptor,interleukin-21 receptor,IL21R

    ID gène
    60504
    UniProt
    Q9JHX3
    Pathways
    Signalistation JAK/STAT
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