LILRA2 Protein (His tag)
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- Antigène Voir toutes LILRA2 Protéines
- LILRA2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 2 (LILRA2))
- Type de proteíne
- Recombinant
- Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette LILRA2 protéine est marqué à la His tag.
- Fonction
- Recombinant Human LILRA2/CD85h Protein
- Séquence
- GHLPKPTLWA EPGSVIIQGS PVTLRCQGSL QAEEYHLYRE NKSASWVRRI QEPGKNGQFP IPSITWEHAG RYHCQYYSHN HSSEYSDPLE LVVTGAYSKP TLSALPSPVV TLGGNVTLQC VSQVAFDGFI LCKEGEDEHP QRLNSHSHAR GWSWAIFSVG PVSPSRRWSY RCYAYDSNSP YVWSLPSDLL ELLVPGVSKK PSLSVQPGPM VAPGESLTLQ CVSDVGYDRF VLYKEGERDF LQRPGWQPQA GLSQANFTLG PVSPSHGGQY RCYSAHNLSS EWSAPSDPLD ILITGQFYDR PSLSVQPVPT VAPGKNVTLL CQSRGQFHTF LLTKEGAGHP PLHLRSEHQA QQNQAEFRMG PVTSAHVGTY RCYSSLSSNP YLLSLPSDPL ELVVSEAAET LSPSQNKTDS TTTSLGQHPQ DYTVEN
- Specificité
- Gly24-Asn449
- Pureté
- > 95 % by SDS-PAGE.
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- < 1 EU/μg of the protein by LAL method.
- Top Product
- Discover our top product LILRA2 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Store the lyophilized protein at -20°C to -80°C for long term.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- Antigène
- LILRA2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 2 (LILRA2))
- Autre désignation
- LILRA2/CD85h (LILRA2 Produits)
- Synonymes
- CD85H Protein, ILT1 Protein, LIR-7 Protein, LIR7 Protein, leukocyte immunoglobulin like receptor A2 Protein, LILRA2 Protein
- Sujet
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Description: LILRA2 (Leukocyte immunoglobulin like receptor A2), also known as CD85H and LIR7 (Leukocyte immunoglobulin-like receptor 7).This encoded protein is an activating receptor that inhibits dendritic cell differentiation and antigen presentation and suppresses the innate immune response. It is an activating receptor highly expressed in inflammatory tissues and is involved in granulocyte and macrophage activation. LILRA2 is primarily expressed on the surface of cells of the innate immunity including monocytes, macrophages, neutrophils, basophils, and eosinophils but not on lymphocytes and NK cells. LILRA2 cross-linking on monocytes induces pro-inflammatory cytokines while inhibiting dendritic cell differentiation and antigen presentation. Diseases associated with LILRA2 include Tuberculoid Leprosy and Leprosy 3.
Name: LILRA2,CD85H,ILT1,LIR-7,LIR7
- ID gène
- 11027
- UniProt
- Q8N149
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