MITF Protein (rFc Tag)

N° du produit ABIN7535744

Détail du produit

Antigène: MITF (Microphthalmia-Associated Transcription Factor (MITF))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette MITF protéine est marqué à la rFc Tag.

Fonction: Recombinant Human MITF Protein

Séquence: HGLSLIPSTG LCSPDLVNRI IKQEPVLENC SQDLLQHHAD LTCTTTLDLT DGTITFNNNL GTGTEANQAY SVPTKMGSKL EDILMDDTLS PVGVTDPLLS SVSPGASKTS SRRSSMSMEE TEHTC

Specificité: His402-Cys526

Pureté: > 95 % by SDS-PAGE.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: <0.1EU/μg

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Stock: -20 °C,-80 °C

Stockage commentaire: Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

Détail du antigène

Antigène: MITF (Microphthalmia-Associated Transcription Factor (MITF))

Autre désignation: MITF (MITF Produits)

Synonymes: MITF Protein, ws2a Protein, mitfa Protein, MITF-A Protein, LOC100313655 Protein, mitfb Protein, CMM8 Protein, MI Protein, WS2 Protein, WS2A Protein, bHLHe32 Protein, BCC2 Protein, Bhlhe32 Protein, Gsfbcc2 Protein, Vitiligo Protein, Wh Protein, bw Protein, mi Protein, vit Protein, MITF-H Protein, MITF-M Protein, CMI9 Protein, melanogenesis associated transcription factor Protein, microphthalmia-associated transcription factor Protein, microphthalmia-associated transcription factor S homeolog Protein, Microphthalmia Protein, MITF Protein, mitf Protein, LOC100313655 Protein, mitf.S Protein, LOC100534525 Protein, MICROP Protein, Mitf Protein

Sujet:

Description: Microphthalmia-associated transcription factor (MITF) is a member of the basic helix-loop-helix leucine zipper (bHLH-Zip) family and functions as the master regulator of the melanocytic lineage.MITF (Microphthalmia-associated transcription factor) is a lineage-specific transcription factor that plays a critical role in melanocyte homeostasis and whose deregulation has been shown to contribute to melanoma disease. Microphthalmia-associated transcription factor (MITF) is expressed in melanomas and has a critical role in melanocyte development and transformation. Because inhibition of MITF inhibits cell growth in melanoma, MITF is a potential therapeutic target molecule. Microphthalmia-associated transcription factor (MITF) regulates the transcription of its target genes by binding to their promoters. Microphthalmia-associated transcription factor (MITF) is a key regulator of differentiation of melanocytes and retinal pigment epithelial cells, but it also has functions in non-pigment cells.

Name: CMM8, COMMAD, MI, WS2, WS2A, bHLHe32,MITF,COMMAD,MI,WS2,WS2A,bHLHe32

ID gène: 4286

UniProt: O75030

Pathways: Chromatin Binding