Nectin-2 Protein (NECTIN2) (His tag)

N° du produit ABIN7535985

Détail du produit

Antigène: Nectin-2 (NECTIN2)

Type de proteíne: Recombinant

Origine: Souris

Source: HEK-293 Cells

Purification/Conjugué: Cette Nectin-2 protéine est marqué à la His tag.

Fonction: Recombinant Mouse Nectin-2/PVRL2/CD112 Protein

Séquence: QDVRVRVLPE VRGRLGGTVE LPCHLLPPTT ERVSQVTWQR LDGTVVAAFH PSFGVDFPNS QFSKDRLSFV RARPETNADL RDATLAFRGL RVEDEGNYTC EFATFPNGTR RGVTWLRVIA QPENHAEAQE VTIGPQSVAV ARCVSTGGRP PARITWISSL GGEAKDTQEP GIQAGTVTII SRYSLVPVGR ADGVKVTCRV EHESFEEPIL LPVTLSVRYP PEVSISGYDD NWYLGRSEAI LTCDVRSNPE PTDYDWSTTS GVFPASAVAQ GSQLLVHSVD RMVNTTFICT ATNAVGTGRA EQVILVRESP STAGAGATGG

Specificité: Gln32-Gly351

Pureté: > 95 % by SDS-PAGE.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: <0.1EU/μg

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Stock: -20 °C,-80 °C

Stockage commentaire: Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

Détail du antigène

Antigène: Nectin-2 (NECTIN2)

Autre désignation: Nectin-2/PVRL2/CD112 (NECTIN2 Produits)

Synonymes: CD112 Protein, HVEB Protein, PRR2 Protein, PVRR2 Protein, AI325026 Protein, AI987993 Protein, Cd112 Protein, MPH Protein, Pvr Protein, Pvs Protein, nectin-2 Protein, nectin cell adhesion molecule 2 Protein, NECTIN2 Protein, Nectin2 Protein

Sujet:

Description: Cluster of Differentiation 112 (CD112), also known as poliovirus receptor related protein 2 (PVRL2 or PRR2), is a single-pass type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. CD112 protein also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and thus is involved in cell to cell spreading of these viruses. CD112 protein has been identified as the ligand for DNAM-1 (CD226), and the interaction of CD226/CD112 protein can induce NK cell- and CD8+?T cell-mediated cytotoxicity and cytokine secretion. CD112 has been regarded as a critical component in allergic reactions, and accordingly may function as a novel target for anti-allergic therapy.

Name: CD112,Nectin-2,PVRL2,PVRL2

ID gène: 19294

UniProt: P32507-1