Neurogranin Protein (NRGN) (Fc Tag)

N° du produit ABIN7536501

Détail du produit

Antigène: Neurogranin (NRGN)

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Neurogranin protéine est marqué à la Fc Tag.

Fonction: Recombinant Human NRGN/Neurogranin Protein

Séquence: DCCTENACSK PDDDILDIPL DDPGANAAAA KIQASFRGHM ARKKIKSGER GRKGPGPGGP GGAGVARGGA GGGPSGD

Specificité: Asp2-Asp78

Pureté: > 97 % by SDS-PAGE.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: < 0.01EU/μg

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of 20 mM Tris 150 mM Nacl, pH 7.5.

Stock: -20 °C,-80 °C

Stockage commentaire: Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

Détail du antigène

Antigène: Neurogranin (NRGN)

Autre désignation: NRGN/Neurogranin (NRGN Produits)

Synonymes: RC3 Protein, hng Protein, 0710001B06Rik Protein, AI838505 Protein, NG Protein, NG/RC3 Protein, Pss1 Protein, R75334 Protein, zgc:158686 Protein, neurogranin Protein, neurogranin (protein kinase C substrate, RC3) b Protein, NRGN Protein, Nrgn Protein, nrgnb Protein

Sujet:

Description: Neurogranin is as a small protein encoded by the NRGN gene. it is a calmodulin-binding protein expressed primarily in the brain, particularly in dendritic spines, and participating in the protein kinase C signaling pathway. Neurogranin is the main postsynaptic protein regulating the availability of calmodulin, binding to it in the absence of calcium. Phosphorylation by protein kinase C lowers its binding ability. It is a potential biomarker of neurological and mental diseases.

Name: RC3, hng,NRGN,Neurogranin

ID gène: 4900

UniProt: Q92686