NTRK3 Protein (Fc Tag,His tag)
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- Antigène Voir toutes NTRK3 Protéines
- NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette NTRK3 protéine est marqué à la Fc Tag,His tag.
- Fonction
- Active Recombinant Human Trk-C/NTRK3 Protein
- Séquence
- CPANCVCSKT EINCRRPDDG NLFPLLEGQD SGNSNGNASI NITDISRNIT SIHIENWRSL HTLNAVDMEL YTGLQKLTIK NSGLRSIQPR AFAKNPHLRY INLSSNRLTT LSWQLFQTLS LRELQLEQNF FNCSCDIRWM QLWQEQGEAK LNSQNLYCIN ADGSQLPLFR MNISQCDLPE ISVSHVNLTV REGDNAVITC NGSGSPLPDV DWIVTGLQSI NTHQTNLNWT NVHAINLTLV NVTSEDNGFT LTCIAENVVG MSNASVALTV YYPPRVVSLE EPELRLEHCI EFVVRGNPPP TLHWLHNGQP LRESKIIHVE YYQEGEISEG CLLFNKPTHY NNGNYTLIAK NPLGTANQTI NGHFLKEPFP ESTDNFILFD EVSPTPPITV THKPEED
- Specificité
- Cys32-Asp428
- Pureté
- > 97 % by SDS-PAGE.
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- < 1.0 EU/μg of the protein by LAL method.
- Biological Activity Comment
- Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human NTF3 at 2 μg/mL (100 μL/well) can bind Recombinant human TrkC with a linear range of 22-90 ng/mL.
- Top Product
- Discover our top product NTRK3 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
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Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
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- Antigène
- NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))
- Autre désignation
- Trk-C/NTRK3 (NTRK3 Produits)
- Synonymes
- TRKC Protein, gp145(trkC) Protein, trkC Protein, AW125844 Protein, Ntrk3_tv3 Protein, TrkC Protein, neurotrophic receptor tyrosine kinase 3 Protein, neurotrophic tyrosine kinase, receptor, type 3 Protein, NTRK3 Protein, Ntrk3 Protein
- Sujet
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Description: NT-3 growth factor receptor also known as neurotrophic tyrosine kinase receptor type 3 or TrkC tyrosine kinase or Trk-C receptor, is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in TrkC encoding gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.
Name: NTRK3,GP145-TrkC,TRKC,gp145(trkC)
- ID gène
- 4916
- UniProt
- Q16288
- Pathways
- Signalisation RTK, Neurotrophin Signaling Pathway, Regulation of Cell Size
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