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AVPR1B Protéine

AVPR1B Origine: Humain Hôte: Mammalian Cells Synthetic Nanodisc
N° du produit ABIN7538138
  • Antigène Voir toutes AVPR1B Protéines
    AVPR1B (Arginine Vasopressin Receptor 1B (AVPR1B))
    Type de proteíne
    Synthetic Nanodisc
    Origine
    • 2
    • 1
    • 1
    Humain
    Source
    • 3
    • 1
    Mammalian Cells
    Fonction
    Human V1BR full length protein-synthetic nanodisc
    Attributs du produit
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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    Discover our top product AVPR1B Protéine
  • Commentaires

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Date de péremption
    12 months
  • Antigène
    AVPR1B (Arginine Vasopressin Receptor 1B (AVPR1B))
    Autre désignation
    V1BR (AVPR1B Produits)
    Synonymes
    LOC443050 Protein, AVPR1B Protein, si:ch211-125a15.3 Protein, AVPR3 Protein, V3/V1b Protein, VIBR Protein, VPR3 Protein, arginine vasopressin receptor 1B Protein, arginine vasopressin receptor 1Ab Protein, AVPR1B Protein, avpr1ab Protein, Avpr1b Protein
    Sujet
    The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008]
    Poids moléculaire
    The human full length V1BR protein has a MW of 47kDa
    UniProt
    P47901
    Pathways
    Regulation of Systemic Arterial Blood Pressure by Hormones
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