AVPR1B Protéine
-
- Antigène Voir toutes AVPR1B Protéines
- AVPR1B (Arginine Vasopressin Receptor 1B (AVPR1B))
- Type de proteíne
- Synthetic Nanodisc
-
Origine
- Humain
-
Source
- Mammalian Cells
- Fonction
- Human V1BR full length protein-synthetic nanodisc
- Attributs du produit
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product AVPR1B Protéine
-
-
- Commentaires
-
Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Date de péremption
- 12 months
-
- Antigène
- AVPR1B (Arginine Vasopressin Receptor 1B (AVPR1B))
- Autre désignation
- V1BR (AVPR1B Produits)
- Synonymes
- LOC443050 Protein, AVPR1B Protein, si:ch211-125a15.3 Protein, AVPR3 Protein, V3/V1b Protein, VIBR Protein, VPR3 Protein, arginine vasopressin receptor 1B Protein, arginine vasopressin receptor 1Ab Protein, AVPR1B Protein, avpr1ab Protein, Avpr1b Protein
- Sujet
- The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008]
- Poids moléculaire
- The human full length V1BR protein has a MW of 47kDa
- UniProt
- P47901
- Pathways
- Regulation of Systemic Arterial Blood Pressure by Hormones
-