CALCRL Protein (AA 23-140) (Fc Tag)

N° du produit ABIN7538151

Détail du produit

Antigène: CALCRL (Calcitonin Receptor-Like (CALCRL))

Type de proteíne: Recombinant

Attributs du protein: AA 23-140

Origine: Humain

Source: Mammalian Cells

Purification/Conjugué: Cette CALCRL protéine est marqué à la Fc Tag.

Fonction: Recombinant human CGRPR Protein with C-terminal human Fc tag

Specificité: CGRPR (Glu23-Asn140) hFc (Glu99-Ala330)

Attributs du produit: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Pureté: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: CALCRL (Calcitonin Receptor-Like (CALCRL))

Autre désignation: CGRPR (CALCRL Produits)

Synonymes: CALCRL Protein, CGRPR Protein, CRLR Protein, AV071593 Protein, CLR Protein, Crlr Protein, RATCRLR Protein, RNCLR Protein, calcitonin receptor like receptor Protein, calcitonin receptor-like Protein, calcitonin receptor like receptor L homeolog Protein, CALCRL Protein, LOC100168906 Protein, calcrl Protein, Calcrl Protein, calcrl.L Protein

Sujet: Enables adrenomedullin binding activity, adrenomedullin receptor activity, and calcitonin gene-related peptide receptor activity. Involved in several processes, including G protein-coupled receptor signaling pathway, cellular response to sucrose stimulus, and receptor internalization. Located in endoplasmic reticulum, endosome, and lysosome. Part of CGRP receptor complex and adrenomedullin receptor complex. Colocalizes with plasma membrane. Implicated in hereditary lymphedema. [provided by Alliance of Genome Resources, Apr 2022]

Poids moléculaire: predicted molecular mass of 39.9 kDa after removal of the signal peptide. The apparent molecular mass of CGRPR-hFc is 35-70 kDa due to glycosylation.

UniProt: Q16602

Pathways: cAMP Metabolic Process