CGRP Protein (AA 83-119) (Fc Tag)

N° du produit ABIN7538155

Détail du produit

Antigène: CGRP (CALCA) (Calcitonin-Related Polypeptide alpha (CALCA))

Type de proteíne: Recombinant

Attributs du protein: AA 83-119

Origine: Souris

Source: Mammalian Cells

Purification/Conjugué: Cette CGRP protéine est marqué à la Fc Tag.

Fonction: Recombinant mouse CGRP protein with C-terminal human Fc tag

Specificité: Mouse CGRP (Ser83-Phe119) hFc (Glu99-Ala330)

Attributs du produit: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Pureté: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: CGRP (CALCA) (Calcitonin-Related Polypeptide alpha (CALCA))

Autre désignation: CGRP (CALCA Produits)

Synonymes: CALC1 Protein, CGRP Protein, CGRP-I Protein, CGRP1 Protein, CT Protein, KC Protein, CALC Protein, CALCA Protein, CALC3 Protein, ci-ct Protein, calca Protein, CA Protein, CGRP-1 Protein, Calc Protein, Calc1 Protein, Cgrp Protein, Ct Protein, Ctn Protein, calcitonin Protein, CAL6 Protein, Cal1 Protein, RATCAL6 Protein, CGRPI Protein, calc Protein, cgrp Protein, zgc:92886 Protein, calcitonin related polypeptide alpha Protein, calcitonin related polypeptide beta Protein, calcitonin-related polypeptide alpha Protein, calcitonin Protein, calcitonin/calcitonin-related polypeptide, alpha Protein, calcitonin-related polypeptide beta Protein, calcitonin gene-related peptide 2 Protein, CALCA Protein, CALCB Protein, ci-ct Protein, calca Protein, Calca Protein, LOC100008771 Protein

Sujet: This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide (CGRP) and katacalcin. Alternative splicing of the mRNA results in multiple variants that encode either calcitonin or CGRP preproproteins. Post-translational processing of the calcitonin and CGRP propeptides results in either calcitonin and katacalcin, or CGRP, respectively. Calcitonin and katacalcin modulate calcium levels in the blood stream. CGRP can function as a vasodilator and play a role in the transmission of pain. The human homolog of CGRP was found to have antimicrobial activity. [provided by RefSeq, Mar 2015]

Poids moléculaire: predicted molecular mass of 29.9 kDa after removal of the signal peptide. The apparent molecular mass of mCGRP-hFc is 25-35 kDa due to glycosylation.

UniProt: Q99JA0

Pathways: Hormone Activity, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, Feeding Behaviour