CD276 Protein (CD276) (AA 29-465) (His tag)
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- Antigène Voir toutes CD276 Protéines
- CD276
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 29-465
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Origine
- Cynomolgus
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Source
- Mammalian Cells
- Purification/Conjugué
- Cette CD276 protéine est marqué à la His tag.
- Fonction
- Recombinant Cynomolgus B7-H3 protein with C-terminal 10xHis tag
- Specificité
- B7-H3 (Leu29-Glu465) 10xHis tag
- Attributs du produit
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Pureté
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product CD276 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Date de péremption
- 12 months
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- Antigène
- CD276
- Autre désignation
- B7-H3 (CD276 Produits)
- Synonymes
- sc:d0645 Protein, zgc:158279 Protein, 6030411F23Rik Protein, AU016588 Protein, B7RP-2 Protein, B7h3 Protein, B7H3 Protein, 4Ig-B7-H3 Protein, B7-H3 Protein, CD276 molecule Protein, CD276 molecule S homeolog Protein, CD276 antigen Protein, Cd276 molecule Protein, CD276 Protein, cd276.S Protein, cd276 Protein, Cd276 Protein
- Sujet
- The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
- Poids moléculaire
- predicted molecular mass of 48.4 kDa after removal of the signal peptide. The apparent molecular mass of cB7-H3-His is 55-100 kDa due to glycosylation.
- NCBI Accession
- XP_015308534
- Pathways
- Cancer Immune Checkpoints
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