CD3 epsilon Protein (CD3E) (AA 22-117) (Fc Tag)
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- Antigène Voir toutes CD3 epsilon (CD3E) Protéines
- CD3 epsilon (CD3E)
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 22-117
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Origine
- Cynomolgus
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Source
- Mammalian Cells
- Purification/Conjugué
- Cette CD3 epsilon protéine est marqué à la Fc Tag.
- Fonction
- Recombinant Cynomolgus CD3E protein with C-terminal human Fc tag
- Specificité
- CD3E (Gln22-Asp117) hFc (Glu99-Ala330)
- Attributs du produit
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Pureté
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product CD3E Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Date de péremption
- 12 months
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- Antigène
- CD3 epsilon (CD3E)
- Autre désignation
- CD3E (CD3E Produits)
- Synonymes
- cd3e Protein, CD3E Protein, t3e Protein, tcre Protein, AI504783 Protein, CD3 Protein, CD3epsilon Protein, T3e Protein, T3E Protein, TCRE Protein, CD3e molecule Protein, CD3 antigen, epsilon polypeptide Protein, cd3e Protein, CD3E Protein, Cd3e Protein
- Sujet
- The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
- Poids moléculaire
- predicted molecular mass of 37.0 kDa after removal of the signal peptide. The apparent molecular mass of cCD3E-hFc is 35-55 kDa due to glycosylation.
- UniProt
- Q95LI5
- Pathways
- TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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