C3AR1 Protéine

N° du produit ABIN7538202

Détail du produit

Antigène: C3AR1 (Complement Component 3a Receptor 1 (C3AR1))

Type de proteíne: Synthetic Nanodisc

Origine: Humain

Source: Mammalian Cells

Fonction: Human C3AR full length protein-synthetic nanodisc

Attributs du produit: Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Information d'application

Commentaires:

Advantages of Synthetic Nanodiscs:

• Highly purified membrane proteins
• High solubility in aqueous solutions
• High stability
• Proteins are in a native membrane environment and remain biologically active
• No detergent and can be used for cell-based assays
• No MSP backbone proteins

Limitations of Synthetic Nanodiscs:

• Intolerant to acids and high concentrations of divalent metal ions

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: C3AR1 (Complement Component 3a Receptor 1 (C3AR1))

Autre désignation: C3AR (C3AR1 Produits)

Synonymes: C3AR Protein, C3a-R Protein, c3ar1 Protein, AZ3B Protein, HNFAG09 Protein, C3a anaphylatoxin chemotactic receptor Protein, complement C3a receptor 1 Protein, complement component 3a receptor 1 Protein, c3ar1 Protein, C3AR1 Protein, C3ar1 Protein

Sujet: C3a is an anaphylatoxin released during activation of the complement system. The protein encoded by this gene is an orphan G protein-coupled receptor for C3a. Binding of C3a by the encoded receptor activates chemotaxis, granule enzyme release, superoxide anion production, and bacterial opsonization. [provided by RefSeq, May 2016]

Poids moléculaire: The human full length C3AR protein has a MW of 53.9kDa

UniProt: Q16581

Pathways: Système du Complément