CFD
Origine: Humain
Hôte: Mammalian Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
CFD
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, Imm, PC
Restrictions
For Research Use only
Format
Lyophilized
Buffer
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Stock
-20 °C,-80 °C
Stockage commentaire
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
ADIPSIN Protein, ADN Protein, DF Protein, PFD Protein, Adn Protein, Df Protein, EVE Protein, CFD Protein, adipsin Protein, pfd Protein, cfdl Protein, wu:fb61f12 Protein, zgc:109940 Protein, 10.5 Protein, 10.9 Protein, 14.10 Protein, 20.35 Protein, CG2328 Protein, Dmel\\CG2328 Protein, E(eve) Protein, Eve Protein, F Protein, V Protein, VI Protein, eve2 Protein, even Protein, l(2)46CFg Protein, l(2)46CFh Protein, l(2)46CFj Protein, l(2)46CFp Protein, l(2)46Ce Protein, l(2)46Cg Protein, complement factor D Protein, complement factor D (adipsin) Protein, complement factor D (adipsin) L homeolog Protein, even skipped Protein, CFD Protein, Cfd Protein, cfd.L Protein, cfd Protein, eve Protein
Sujet
This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease. [provided by RefSeq, Nov 2015]
Poids moléculaire
predicted molecular mass of 50.5 kDa after removal of the signal peptide. The apparent molecular mass of CFD-hFc is 55-70 kDa due to glycosylation.