Contactin 1 Protein (CNTN1)

N° du produit ABIN7538207

Détail du produit

Antigène: Contactin 1 (CNTN1)

Type de proteíne: Synthetic Nanodisc

Origine: Humain

Source: Mammalian Cells

Fonction: Human GP135 full length protein-synthetic nanodisc

Attributs du produit: Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Information d'application

Commentaires:

Advantages of Synthetic Nanodiscs:

• Highly purified membrane proteins
• High solubility in aqueous solutions
• High stability
• Proteins are in a native membrane environment and remain biologically active
• No detergent and can be used for cell-based assays
• No MSP backbone proteins

Limitations of Synthetic Nanodiscs:

• Intolerant to acids and high concentrations of divalent metal ions

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: Contactin 1 (CNTN1)

Autre désignation: GP135 (CNTN1 Produits)

Synonymes: F3 Protein, GP135 Protein, AW495098 Protein, CNTN Protein, F3cam Protein, F3/F11 Protein, cntn-A Protein, F11 Protein, CNTN1 Protein, cntn1 Protein, contactin 1 Protein, contactin 1 L homeolog Protein, contactin 1a Protein, CNTN1 Protein, Cntn1 Protein, cntn1.L Protein, cntn1a Protein

Sujet: Orphan receptor. Has spontaneous activity for beta-arrestin recruitment (PubMed:28827538). Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization (PubMed:28827538).[UniProtKB/Swiss-Prot Function]

Poids moléculaire: The human full length GP135 protein has a MW of 51.7kDa

UniProt: Q8IZ08