FPR3 Protéine

N° du produit ABIN7538240

Détail du produit

Antigène: FPR3 (Formyl Peptide Receptor 3 (FPR3))

Type de proteíne: Synthetic Nanodisc

Origine: Humain

Source: Mammalian Cells

Fonction: Human FPR3 full length protein-synthetic nanodisc

Attributs du produit: Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Information d'application

Commentaires:

Advantages of Synthetic Nanodiscs:

• Highly purified membrane proteins
• High solubility in aqueous solutions
• High stability
• Proteins are in a native membrane environment and remain biologically active
• No detergent and can be used for cell-based assays
• No MSP backbone proteins

Limitations of Synthetic Nanodiscs:

• Intolerant to acids and high concentrations of divalent metal ions

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: FPR3 (Formyl Peptide Receptor 3 (FPR3))

Autre désignation: FPR3 (FPR3 Produits)

Synonymes: RGD1566044 Protein, FML2_HUMAN Protein, FMLPY Protein, FPRH1 Protein, FPRH2 Protein, FPRL2 Protein, RMLP-R-I Protein, ALX Protein, Fpr-rs1 Protein, Fpr-s1 Protein, Fprl1 Protein, LXA4-R Protein, Lxa4r Protein, FMLP-R-II Protein, formyl peptide receptor 3 Protein, Fpr3 Protein, FPR3 Protein

Sujet: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.[UniProtKB/Swiss-Prot Function]

Poids moléculaire: The human full length FPR3 protein has a MW of 40kDa

UniProt: P25089