FZD9 Protéine

N° du produit ABIN7538250

Détail du produit

Antigène: FZD9 (Frizzled Family Receptor 9 (FZD9))

Type de proteíne: Synthetic Nanodisc

Origine: Humain

Source: Mammalian Cells

Fonction: Human FZD9 full length protein-synthetic nanodisc

Attributs du produit: Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Information d'application

Commentaires:

Advantages of Synthetic Nanodiscs:

• Highly purified membrane proteins
• High solubility in aqueous solutions
• High stability
• Proteins are in a native membrane environment and remain biologically active
• No detergent and can be used for cell-based assays
• No MSP backbone proteins

Limitations of Synthetic Nanodiscs:

• Intolerant to acids and high concentrations of divalent metal ions

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: FZD9 (Frizzled Family Receptor 9 (FZD9))

Autre désignation: FZD9 (FZD9 Produits)

Synonymes: CD349 Protein, FZD3 Protein, mfz9 Protein, Fz-9 Protein, cFz-9 Protein, fz11 Protein, fzd9 Protein, fzx Protein, hm:zehl0603 Protein, zehl0603 Protein, zg11 Protein, frizzled class receptor 9 Protein, frizzled class receptor 9a Protein, frizzled class receptor 9b Protein, FZD9 Protein, Fzd9 Protein, fzd9a Protein, fzd9b Protein

Sujet: Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD9 gene is located within the Williams syndrome common deletion region of chromosome 7, and heterozygous deletion of the FZD9 gene may contribute to the Williams syndrome phenotype. FZD9 is expressed predominantly in brain, testis, eye, skeletal muscle, and kidney. [provided by RefSeq, Jul 2008]

Poids moléculaire: The human full length FZD9 protein has a MW of 64.5kDa

UniProt: O00144

Pathways: Signalisation WNT