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GPR3 Protéine

GPR3 Origine: Humain Hôte: Mammalian Cells Synthetic Nanodisc
N° du produit ABIN7538268
  • Antigène Voir toutes GPR3 Protéines
    GPR3 (G Protein-Coupled Receptor 3 (GPR3))
    Type de proteíne
    Synthetic Nanodisc
    Origine
    • 3
    • 2
    • 1
    Humain
    Source
    • 2
    • 2
    • 1
    Mammalian Cells
    Fonction
    Human GPR3 full length protein-synthetic nanodisc
    Attributs du produit
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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    Discover our top product GPR3 Protéine
  • Commentaires

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Date de péremption
    12 months
  • Antigène
    GPR3 (G Protein-Coupled Receptor 3 (GPR3))
    Autre désignation
    GPR3 (GPR3 Produits)
    Synonymes
    GPR3 Protein, ACCA Protein, Gpcr3 Protein, Gpcr20 Protein, Gpcr21 Protein, G protein-coupled receptor 3 Protein, G-protein coupled receptor 3 Protein, GPR3 Protein, Gpr3 Protein
    Sujet
    This gene is a member of the G protein-coupled receptor family and is found in the cell membrane. G protein-coupled receptors, characterized by a seven transmembrane domain motif, are involved in translating outside signals into G protein mediated intracellular effects. The encoded protein activates adenylate cyclase and modulates amyloid-beta production in a mouse model, suggesting that it may play a role in Alzheimer's disease. [provided by RefSeq, Oct 2012]
    Poids moléculaire
    The human full length GPR3 protein has a MW of 35kDa
    UniProt
    P46089
    Pathways
    cAMP Metabolic Process
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