GPR37 Protéine

N° du produit ABIN7538273

Détail du produit

Antigène: GPR37 (G Protein-Coupled Receptor 37 (Endothelin Receptor Type B-Like) (GPR37))

Type de proteíne: Synthetic Nanodisc

Origine: Humain

Source: Mammalian Cells

Fonction: Human GPR37 full length protein-synthetic nanodisc

Attributs du produit: Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Information d'application

Commentaires:

Advantages of Synthetic Nanodiscs:

• Highly purified membrane proteins
• High solubility in aqueous solutions
• High stability
• Proteins are in a native membrane environment and remain biologically active
• No detergent and can be used for cell-based assays
• No MSP backbone proteins

Limitations of Synthetic Nanodiscs:

• Intolerant to acids and high concentrations of divalent metal ions

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: GPR37 (G Protein-Coupled Receptor 37 (Endothelin Receptor Type B-Like) (GPR37))

Autre désignation: GPR37 (GPR37 Produits)

Synonymes: ACCA Protein, EDNRBL Protein, PAELR Protein, hET(B)R-LP Protein, AI848630 Protein, Pael-R Protein, Ednrbl Protein, G protein-coupled receptor 3 Protein, G protein-coupled receptor 37 Protein, GPR3 Protein, GPR37 Protein, Gpr37 Protein

Sujet: This gene is a member of the G protein-coupled receptor family. The encoded protein contains seven transmembrane domains and is found in cell and endoplasmic reticulum membranes. G protein-coupled receptors are involved in translating outside signals into G protein mediated intracellular effects. This gene product interacts with Parkin and is involved in juvenile Parkinson disease. [provided by RefSeq, Oct 2012]

Poids moléculaire: The human full length GPR37 protein has a MW of 67.1kDa

UniProt: O15354