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GABBR2 Protéine

GABBR2 Origine: Humain Hôte: Mammalian Cells Synthetic Nanodisc
N° du produit ABIN7538298
  • Antigène Voir toutes GABBR2 Protéines
    GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))
    Type de proteíne
    Synthetic Nanodisc
    Origine
    • 3
    • 1
    Humain
    Source
    • 2
    • 1
    Mammalian Cells
    Fonction
    Human GABR2 full length protein-synthetic nanodisc
    Attributs du produit
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
    Top Product
    Discover our top product GABBR2 Protéine
  • Commentaires

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Date de péremption
    12 months
  • Antigène
    GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))
    Autre désignation
    GABR2 (GABBR2 Produits)
    Synonymes
    Gpr51 Protein, GABABR2 Protein, GPR51 Protein, GPRC3B Protein, HG20 Protein, HRIHFB2099 Protein, Gb2 Protein, Gm425 Protein, GABA(B)R2 Protein, si:dkey-190l1.2 Protein, gamma-aminobutyric acid type B receptor subunit 2 Protein, gamma-aminobutyric acid (GABA) B receptor, 2 Protein, gamma-aminobutyric acid (GABA) B receptor, 2 S homeolog Protein, GABBR2 Protein, LOC100448699 Protein, gabbr2 Protein, Gabbr2 Protein, gabbr2.S Protein
    Sujet
    The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010]
    Poids moléculaire
    The human full length GABR2 protein has a MW of 105.8kDa
    UniProt
    O75899
    Pathways
    cAMP Metabolic Process
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