IGF1R Protein (AA 31-936) (His tag)

N° du produit ABIN7538331

Détail du produit

Antigène: IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

Type de proteíne: Recombinant

Attributs du protein: AA 31-936

Origine: Souris

Source: Mammalian Cells

Purification/Conjugué: Cette IGF1R protéine est marqué à la His tag.

Fonction: Recombinant mouse IGF-1R protein with C-terminal 6xHis tag

Specificité: Mouse IGF-1R (Glu31-His936) 6xHis tag

Attributs du produit: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Pureté: The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

Autre désignation: IGF-1R (IGF1R Produits)

Synonymes: CMT2N Protein, CD221 Protein, IGFIR Protein, IGFR Protein, JTK13 Protein, IGFIRC Protein, IGFR1 Protein, IGF-1R Protein, IGF1R Protein, DKFZp469I0618 Protein, igf-1r Protein, xIGF-1R Protein, xIGFR Protein, xigf1r Protein, A330103N21Rik Protein, D930020L01 Protein, hyft Protein, igf-ir Protein, IGF-IR Protein, IGF-IRb Protein, wu:fb03h06 Protein, IGF-IRa Protein, sb:eu1090 Protein, wu:fi20b10 Protein, alanyl-tRNA synthetase Protein, insulin like growth factor 1 receptor Protein, insulin-like growth factor 1 receptor Protein, insulin-like growth factor 1 Protein, insulin-like growth factor I receptor Protein, insulin like growth factor 1 receptor S homeolog Protein, insulin-like growth factor 1b receptor Protein, insulin-like growth factor 1a receptor Protein, AARS Protein, IGF1R Protein, Igf1r Protein, igf1r Protein, Igf1 Protein, LOC780503 Protein, LOC100136427 Protein, igf1r.S Protein, igf1rb Protein, igf1ra Protein

Sujet: Enables insulin-like growth factor binding activity. Involved in several processes, including adrenal gland development, positive regulation of cold-induced thermogenesis, and positive regulation of meiotic cell cycle. Acts upstream of or within several processes, including gland development, peptidyl-tyrosine autophosphorylation, and regulation of intracellular signal transduction. Located in T-tubule. Is integral component of membrane. Is expressed in several structures, including alimentary system, brain, genitourinary system, limb, and lung. Human ortholog(s) of this gene implicated in several diseases, including dementia (multiple), kidney cancer (multiple), liver disease (multiple), nervous system cancer (multiple), and neurodegenerative disease (multiple). Orthologous to human IGF1R (insulin like growth factor 1 receptor). [provided by Alliance of Genome Resources, Apr 2022]

Poids moléculaire: predicted molecular mass of 104.5 kDa after removal of the signal peptide.

UniProt: Q60751

Pathways: Signalisation RTK, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy