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LPAR1 Protéine

LPAR1 Origine: Humain Hôte: Mammalian Cells Synthetic Nanodisc
N° du produit ABIN7538364
  • Antigène Voir toutes LPAR1 Protéines
    LPAR1 (Lysophosphatidic Acid Receptor 1 (LPAR1))
    Type de proteíne
    Synthetic Nanodisc
    Origine
    • 4
    • 1
    Humain
    Source
    • 2
    • 2
    • 1
    Mammalian Cells
    Fonction
    Human LPAR1 full length protein-synthetic nanodisc
    Attributs du produit
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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  • Commentaires

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Date de péremption
    12 months
  • Antigène
    LPAR1 (Lysophosphatidic Acid Receptor 1 (LPAR1))
    Autre désignation
    LPAR1 (LPAR1 Produits)
    Synonymes
    EDG2 Protein, GPR26 Protein, Gpcr26 Protein, LPA1 Protein, Mrec1.3 Protein, VZG1 Protein, edg-2 Protein, rec.1.3 Protein, vzg-1 Protein, Edg2 Protein, EDG-2 Protein, 5031439C20 Protein, AI326300 Protein, Kdt2 Protein, lpA1 Protein, edg2 Protein, si:dz22b13.1 Protein, si:dz46m7.1 Protein, zgc:92157 Protein, LPA receptor 1-A Protein, LPA-1-A Protein, gpr26 Protein, lpa1 Protein, lpa1r Protein, lpa1r1 Protein, lpar1 Protein, lpar1-a Protein, lpar1-b Protein, vzg1 Protein, xLPA1-1 Protein, LPA receptor 1-B Protein, LPA-1-B Protein, edg2-A Protein, xLPA1-2 Protein, xlpa1R Protein, lysophosphatidic acid receptor 1 Protein, lysophosphatidic acid receptor 1 S homeolog Protein, lysophosphatidic acid receptor 1 L homeolog Protein, LPAR1 Protein, Lpar1 Protein, lpar1 Protein, lpar1.S Protein, lpar1.L Protein
    Sujet
    The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Many transcript variants encoding a few different isoforms have been identified for this gene. [provided by RefSeq, Oct 2020]
    Poids moléculaire
    The human full length LPAR1 protein has a MW of 41.1kDa
    UniProt
    Q92633
    Pathways
    Myometrial Relaxation and Contraction, Smooth Muscle Cell Migration
Support technique