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MRGPRD Protéine

MRGPRD Origine: Humain Hôte: Mammalian Cells Synthetic Nanodisc
N° du produit ABIN7538371
  • Antigène Voir toutes MRGPRD Protéines
    MRGPRD (MAS-Related GPR, Member D (MRGPRD))
    Type de proteíne
    Synthetic Nanodisc
    Origine
    • 2
    • 1
    Humain
    Source
    • 2
    • 1
    Mammalian Cells
    Fonction
    Human MRGRD full length protein-synthetic nanodisc
    Attributs du produit
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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    Discover our top product MRGPRD Protéine
  • Commentaires

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Date de péremption
    12 months
  • Antigène
    MRGPRD (MAS-Related GPR, Member D (MRGPRD))
    Autre désignation
    MRGRD (MRGPRD Produits)
    Synonymes
    MRGD Protein, TGR7 Protein, Gm499 Protein, MrgD Protein, Mrgd Protein, MAS related GPR family member D Protein, mas-related G-protein coupled receptor member D Protein, MAS-related GPR, member D Protein, MRGPRD Protein, LOC615853 Protein, Mrgprd Protein
    Sujet
    May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2 ) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).[UniProtKB/Swiss-Prot Function]
    Poids moléculaire
    The human full length MRGRD protein has a MW of 36.1kDa
    UniProt
    Q8TDS7
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