MC5 Receptor Protéine

N° du produit ABIN7538386

Détail du produit

Antigène: MC5 Receptor (MC5R) (Melanocortin 5 Receptor (MC5R))

Type de proteíne: Synthetic Nanodisc

Origine: Humain

Source: Mammalian Cells

Fonction: Human MC5R full length protein-synthetic nanodisc

Attributs du produit: Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Information d'application

Commentaires:

Advantages of Synthetic Nanodiscs:

• Highly purified membrane proteins
• High solubility in aqueous solutions
• High stability
• Proteins are in a native membrane environment and remain biologically active
• No detergent and can be used for cell-based assays
• No MSP backbone proteins

Limitations of Synthetic Nanodiscs:

• Intolerant to acids and high concentrations of divalent metal ions

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: MC5 Receptor (MC5R) (Melanocortin 5 Receptor (MC5R))

Autre désignation: MC5R (MC5R Produits)

Synonymes: MC2 Protein, MC5R Protein, MC5 Protein, mc5br Protein, mc5ra Protein, zMC5b Protein, zgc:194217 Protein, mc5ar Protein, mc5rb Protein, zMC5a Protein, melanocortin 5 receptor Protein, melanocortin 5b receptor Protein, melanocortin 5a receptor Protein, MC5R Protein, Mc5r Protein, mc5r Protein, mc5rb Protein, mc5ra Protein

Sujet: This gene encodes a member of the seven-pass transmembrane G protein-coupled melanocortin receptor protein family that stimulate cAMP signal transduction. The encoded protein is a receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone and is suggested to play a role in sebum generation. [provided by RefSeq, Jun 2010]

Poids moléculaire: The human full length MC5R protein has a MW of 36.6kDa

UniProt: P33032

Pathways: cAMP Metabolic Process