OR1E2 Protéine

N° du produit ABIN7538425

Détail du produit

Antigène: OR1E2 (Olfactory Receptor, Family 1, Subfamily E, Member 2 (OR1E2))

Type de proteíne: Synthetic Nanodisc

Origine: Humain

Source: Mammalian Cells

Fonction: Human OR1E2 full length protein-synthetic nanodisc

Attributs du produit: Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Information d'application

Commentaires:

Advantages of Synthetic Nanodiscs:

• Highly purified membrane proteins
• High solubility in aqueous solutions
• High stability
• Proteins are in a native membrane environment and remain biologically active
• No detergent and can be used for cell-based assays
• No MSP backbone proteins

Limitations of Synthetic Nanodiscs:

• Intolerant to acids and high concentrations of divalent metal ions

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: OR1E2 (Olfactory Receptor, Family 1, Subfamily E, Member 2 (OR1E2))

Autre désignation: OR1E2 (OR1E2 Produits)

Synonymes: PTOR1E4 Protein, OR17-135 Protein, OR17-93 Protein, OR1E4 Protein, OR1E7 Protein, OST529 Protein, olfactory receptor PTOR1E4 Protein, olfactory receptor family 1 subfamily E member 2 Protein, OR1E2 Protein

Sujet: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

Poids moléculaire: The human full length OR1E2 protein has a MW of 36.4kDa

UniProt: P47887