TNFRSF1B Protein (AA 23-258) (His tag)

N° du produit ABIN7538581

Détail du produit

Antigène: TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))

Type de proteíne: Recombinant

Attributs du protein: AA 23-258

Origine: Souris

Source: Mammalian Cells

Purification/Conjugué: Cette TNFRSF1B protéine est marqué à la His tag.

Fonction: Recombinant mouse TNFRSF1B protein with C-terminal 6xHis tag

Specificité: Mouse TNFRSF1B (Val23-Gly258) 6xHis tag

Attributs du produit: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Pureté: The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))

Autre désignation: TNFRSF1B (TNFRSF1B Produits)

Synonymes: CD120b Protein, TBPII Protein, TNF-R-II Protein, TNF-R75 Protein, TNFBR Protein, TNFR1B Protein, TNFR2 Protein, TNFR80 Protein, p75 Protein, p75TNFR Protein, TNF-RII/TNFRSF1B Protein, TNFR-II Protein, TNFRSF1B Protein, TNF-R2 Protein, TNF-alphaR2 Protein, TNFRII Protein, TNFalpha-R2 Protein, Tnfr-1 Protein, Tnfr2 Protein, rank Protein, zgc:163064 Protein, TNF receptor superfamily member 1B Protein, tumor necrosis factor receptor superfamily, member 1b Protein, tumor necrosis factor receptor superfamily, member 1B Protein, TNFRSF1B Protein, Tnfrsf1b Protein, tnfrsf1b Protein

Sujet: Enables tumor necrosis factor-activated receptor activity. Involved in several processes, including negative regulation of extracellular matrix constituent secretion, regulation of nervous system development, and semi-lunar valve development. Acts upstream of or within several processes, including RNA destabilization, apoptotic signaling pathway, and negative regulation of inflammatory response. Located in membrane raft. Is expressed in several structures, including blood, dorsal aorta, extraembryonic component, genitourinary system, and liver. Human ortholog(s) of this gene implicated in several diseases, including Parkinsonism, acne, bone disease (multiple), glomerulonephritis (multiple), and lung disease (multiple). Orthologous to human TNFRSF1B (TNF receptor superfamily member 1B). [provided by Alliance of Genome Resources, Apr 2022]

Poids moléculaire: predicted molecular mass of 26.2 kDa after removal of the signal peptide. The apparent molecular mass of mTNFRSF1B-His is 25-55 kDa due to glycosylation.

UniProt: P25119

Pathways: Signalisation NF-kappaB, Apoptose, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Ubiquitin Proteasome Pathway