IL-3 Protéine
-
- Antigène Voir toutes IL-3 Protéines
- IL-3 (Interleukin 3 (IL-3))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
-
Origine
- Souris
-
Source
- Escherichia coli (E. coli)
- Fonction
- IL-3
- Séquence
- ASISGRDTHR LTRTLNCSSI VKEIIGKLPE PELKTDDEGP SLRNKSFRRV NLSKFVESQG EVDPEDRYVI KSNLQKLNCC LPTSANDSAL PGVFIRDLDD FRKKLRFYMV HLNDLETVLT SRPPQPASGS VSPNRGTVEC
- Specificité
- Chromosomal location:11 B1, 11 28.5 cM
- Réactivité croisée
- Bactéries, Gerbille, Humain, Singe, Souris, Rat
- Attributs du produit
- Length (aa):140
- Pureté
- > 98 % by SDS-PAGE and Coomassie stain
- niveau d'endotoxine
- < 0.1 ng/μg of protein (<1EU/μg)
- Top Product
- Discover our top product IL-3 Protéine
-
-
- Indications d'application
- The ED50 as determined by the dose-dependent stimulation of the proliferation of murine NFS-60 cells is in the range of 20-100 pg/mL.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- water
- Buffer
- PBS
-
- Antigène
- IL-3 (Interleukin 3 (IL-3))
- Autre désignation
- IL-3 (IL-3 Produits)
- Synonymes
- BPA Protein, Csfmu Protein, HCGF Protein, Il-3 Protein, MCGF Protein, PSF Protein, IL-3 Protein, MULTI-CSF Protein, interleukin 3 Protein, interleukin 3 (colony-stimulating factor, multiple) Protein, Il3 Protein, IL3 Protein
- Sujet
- Il3, BPA, PSF, HCGF, Il-3, MCGF, Csfmu,IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine. Recombinant murine IL-3 is a 15.1 kDa globular protein containing 135 amino acid residues.
- Poids moléculaire
- 15.8 kDa
- ID gène
- 16187
- NCBI Accession
- NM_010556, NP_034686
- UniProt
- P01586
- Pathways
- Signalistation JAK/STAT, Regulation of Carbohydrate Metabolic Process, Autophagy
-