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IL-3 Protéine

IL-3 Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 98 % by SDS-PAGE and Coomassie stain Active
N° du produit ABIN7539337
  • Antigène Voir toutes IL-3 Protéines
    IL-3 (Interleukin 3 (IL-3))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Origine
    • 22
    • 11
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Souris
    Source
    • 26
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Fonction
    IL-3
    Séquence
    ASISGRDTHR LTRTLNCSSI VKEIIGKLPE PELKTDDEGP SLRNKSFRRV NLSKFVESQG EVDPEDRYVI KSNLQKLNCC LPTSANDSAL PGVFIRDLDD FRKKLRFYMV HLNDLETVLT SRPPQPASGS VSPNRGTVEC
    Specificité
    Chromosomal location:11 B1, 11 28.5 cM
     Réactivité croisée
    Bactéries, Gerbille, Humain, Singe, Souris, Rat
    Attributs du produit
    Length (aa):140
    Pureté
    > 98 % by SDS-PAGE and Coomassie stain
    niveau d'endotoxine
    < 0.1 ng/μg of protein (<1EU/μg)
    Top Product
    Discover our top product IL-3 Protéine
  • Indications d'application
    The ED50 as determined by the dose-dependent stimulation of the proliferation of murine NFS-60 cells is in the range of 20-100 pg/mL.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    water
    Buffer
    PBS
  • Antigène
    IL-3 (Interleukin 3 (IL-3))
    Autre désignation
    IL-3 (IL-3 Produits)
    Synonymes
    BPA Protein, Csfmu Protein, HCGF Protein, Il-3 Protein, MCGF Protein, PSF Protein, IL-3 Protein, MULTI-CSF Protein, interleukin 3 Protein, interleukin 3 (colony-stimulating factor, multiple) Protein, Il3 Protein, IL3 Protein
    Sujet
    Il3, BPA, PSF, HCGF, Il-3, MCGF, Csfmu,IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine. Recombinant murine IL-3 is a 15.1 kDa globular protein containing 135 amino acid residues.
    Poids moléculaire
    15.8 kDa
    ID gène
    16187
    NCBI Accession
    NM_010556, NP_034686
    UniProt
    P01586
    Pathways
    Signalistation JAK/STAT, Regulation of Carbohydrate Metabolic Process, Autophagy
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