KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKSNNRQVC IDPKLKWIQE YLDKALNKRL KM
Attributs du produit
A single non-glycosylated polypeptide chain containing 72 amino acids. Biological Activity: Fully biologically active when compared to standard. Determined by its ability to chemoattract human monocytes using a concentration range of 100.0-200.0 ng/ml.
Pureté
> 97 % by SDS-PAGE and HPLC analyses.
Stérilité
0.2 μm filtered
niveau d'endotoxine
Less than 1EU/µg of rRtSDF-1beta/CXCL12 as determined by LAL method.
TMPRSS15
Origine: Humain
Hôte: CHO Cells
Recombinant
< 90 % by SDS-PAGE gel and HPLC analyses.
Active
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20° C. Further dilutions should be made in appropriate buffered solutions.
Buffer
Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4, 150mM NaCl.
SDF-1alpha and beta are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1alpha and beta chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV suppressive activity in cells expressing the CXCR4 receptor.