TNNI
Origine: Souris
Hôte: Souris
Native
> 90 % pure
Indications d'application
Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions
For Research Use only
Format
Liquid
Buffer
Supplied as a liquid in 8 M Urea buffer with 30 mM NaCl, 50 mM Tris. HCl, 15 mM beta-mercaptoethanol, 1 mM EGTA, pH 8.0
Précaution d'utilisation
Donor samples were tested and found to be negative for HBsAg, Anti-HIV-1/HIV-2, & HCV. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles.
Stock
-20 °C/-80 °C
Stockage commentaire
Store at -20 °C to -70 °C,
Mulvaney, Cole, Kniller, Malito, Tamanaha, Rife, Stanton, Whitman: "Rapid, femtomolar bioassays in complex matrices combining microfluidics and magnetoelectronics." dans: Biosensors & bioelectronics, Vol. 23, Issue 2, pp. 191-200, (2007) (PubMed).
CG7178 Protein, DROTROPONI Protein, DmTpnI Protein, Dmel\\CG7178 Protein, HDP Protein, HL-I Protein, HL08042 Protein, HLI Protein, Tn I Protein, TnI Protein, TpnI Protein, WupA Protein, hdp Protein, hdp2 Protein, wup-A Protein, tni Protein, wings up A Protein, troponin I Protein, putative troponin I Protein, wupA Protein, tni Protein, LOC5574015 Protein, Smp_059170.1 Protein
Sujet
Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle. The letter I is given due to its inhibitory character. Description: Human cardiac tissue.