Troponin I Protein (TNNI)

N° du produit ABIN934731

Détail du produit

Antigène: Troponin I (TNNI)

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Attributs du produit: Purified Recombinant Human Troponin I protein (Cardiac)
Expression System: E.coli

Pureté: > 98 % pure

Information d'application

Indications d'application: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Stockage

Buffer: Supplied in 6 M Urea, 56 M Tris, pH 8.0

Précaution d'utilisation: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C

Stockage commentaire: Aliquot and store at -25 °C.

Référence

Mulvaney, Cole, Kniller, Malito, Tamanaha, Rife, Stanton, Whitman: "Rapid, femtomolar bioassays in complex matrices combining microfluidics and magnetoelectronics." dans: Biosensors & bioelectronics, Vol. 23, Issue 2, pp. 191-200, (2007) (PubMed).

Détail du antigène

Antigène: Troponin I (TNNI)

Autre désignation: Troponin I (TNNI Produits)

Synonymes: CG7178 Protein, DROTROPONI Protein, DmTpnI Protein, Dmel\\CG7178 Protein, HDP Protein, HL-I Protein, HL08042 Protein, HLI Protein, Tn I Protein, TnI Protein, TpnI Protein, WupA Protein, hdp Protein, hdp2 Protein, wup-A Protein, tni Protein, wings up A Protein, troponin I Protein, putative troponin I Protein, wupA Protein, tni Protein, LOC5574015 Protein, Smp_059170.1 Protein

Sujet: Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle. The letter I is given due to its inhibitory character.
Description: E.coli.

Poids moléculaire: 24 kDa