CEA Protéine

N° du produit ABIN934752

Détail du produit

Antigène: CEA (Carcinoembryonic Antigen Gene Family (CEA))

Type de proteíne: Native

Origine: Humain

Source: Human

Application: Control Peptide (CP)

Attributs du produit: Highly purified Human CEA protein
Protein Source: Human colon adenocarcinoma cell line

Pureté: Highly pure

Information d'application

Indications d'application: This highly purified product can be used as an immunogen or for labeling and standards, calibrators but is primarily used for multiple analyte controls.

Restrictions: For Research Use only

Stockage

Buffer: PBS pH 7.4, with 0.1 % NaN3.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Référence

Lima, Jenkins, Guerrero, Triozzi, Shaw, Strong: "A DNA vaccine encoding genetic fusions of carcinoembryonic antigen (CEA) and granulocyte/macrophage colony-stimulating factor (GM-CSF)." dans: Vaccine, Vol. 23, Issue 10, pp. 1273-83, (2005) (PubMed).

Détail du antigène

Antigène: CEA (Carcinoembryonic Antigen Gene Family (CEA))

Autre désignation: CEA (CEA Produits)

Sujet: Carcinoembryonic antigen (CEA) is a glycoprotein involved in cell adhesion. It is normally produced during fetal development, but the production of CEA stops before birth. Therefore, it is not usually present in the blood of healthy adults, although levels are raised in heavy smokers. CEA is a glycosyl phosphatidyl inositol (GPI)-cell surface anchored glycoprotein whose specialized sialofucosylated glycoforms serve as functional colon carcinoma L-selectin and E-selectin ligands, which may be critical to the metastatic dissemination of colon carcinoma cells.
Description: Human colon adenocarcinoma cell line.
Alternative Names: Carcinoembryonic antigen protein