TCL1A Protein (AA 1-114)

N° du produit ABIN935060

Détail du produit

Antigène: TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))

Type de proteíne: Recombinant

Attributs du protein: AA 1-114

Origine: Humain

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Séquence: MAECPTLGEA VTDHPDRLWA WEKFVYLDEK QHAWLPLTIE IKDRLQLRVL LRREDVVLGR PMTPTQIGPS LLPIMWQLYP DGRYRSSDSS FWRLVYHIKI DGVEDMLLEL LPDD

Attributs du produit: Purified recombinant Human TCL1 A protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher.

Pureté: > 90 % pure

Information d'application

Indications d'application: TCL1A protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Supplied as a liquid in 50 mM Tris-HCl buffer, pH 7.5, containing 10 % glycerol.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: RT/-20 °C

Stockage commentaire: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Détail du antigène

Antigène: TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))

Autre désignation: TCL1A (TCL1A Produits)

Synonymes: TCL1A Protein, Tcl1a Protein, TCL1 Protein, Tcl1 Protein, T-cell leukemia/lymphoma 1A Protein, T cell lymphoma breakpoint 1 Protein, TCL1A Protein, Tcl1 Protein, Tcl1a Protein

Sujet: TCL1A, also known as T-cell leukemia/lymphoma 1A, is a protein with a suggested role in intracellular regulation of T cell signaling. TCL1A binds to the pleckstrin homology domain of Akt (protein kinase B) family proteins, which facilitates Akt dimerization and activity. By increasing Akt activity TCL1A may enhance the serine/threonine phosphorylation of major Akt signaling substrates, such as Ikk complex, mTOR, BAD, p70S6 kinase, FOXO transcription factors, and GSK3b. These substrates regulate cellular differentiation, growth, survival, and metabolism. Recombinant TCL1A protein was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: TCL 1 protein protein, T cell leukemia 1 protein, TCLA-1 protein, TCL1A, TCLA 1, TCL-1 protein, TCL1A protein, TCL1 oncogene protein, P14 TCL1 protein protein, protein p14TCL1 protein, TCL1 PEN protein, TCLA 1 protein, Oncogene TCL1 protein, T-cell leukemia/lymphoma 1A anti TCL1A protein, T cell lymphoma 1A protein, TCL1A., TCL1 protein, T cell lymphoma 1 protein, P14 TCL1 protein, TCLA-1

Poids moléculaire: 13.4 kDa (114 AA)

Pathways: Stem Cell Maintenance