Purified recombinant Human Angiopoietin 1 protein Expression System: HeLa cells Bioactivity: Determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC).
Angiopoietin-1 (Ang-1) is a secreted ligand for Tie-2, a tyrosine-kinase receptor expressed primarily on vascular endothelial cells and early hematopoietic cells. Ang-1/ Tie-2 signaling promotes angiogenesis during the development, remodeling, and repair of the vascular system. Transgenic mice lacking expression of either Ang-1 or Tie-2 fail to develop a fully functional cardiovascular system and die before birth. Alternative Names: AGPT protein, ANGPT 1 protein, ANG1 protein, ANG 1 protein, KIAA0003 protein, Angiopoietin 1, Angiopoietin 1, ANGPT1 protein, AGP1 protein, AGP 1 protein, Angiopoietin -1, Angiopoietin -1 protein, Angiopoietin1 protein, Angiopoietin 1 protein