GDF11 Protéine
GDF11
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 98 % pure
Active
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- Antigène Voir toutes GDF11 Protéines
- GDF11 (Growth Differentiation Factor 11 (GDF11))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Séquence
- NLGLDCDEHS SESRCCRYPL TVDFEAFGWD WIIAPKRYKA NYCSGQCEYM FMQKYPHTHL VQQANPRGSA GPCCTPTKMS PINMLYFNDK QQIIYGKIPG MVVDRCGCS
- Attributs du produit
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Purified recombinant Human GDF11 protein
Expression System: E.coli
Bioactivity: The ED50 was determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells. The expected ED50 for this effect is 0.08-0.10 µg/mL. - Pureté
- > 98 % pure
- niveau d'endotoxine
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product GDF11 Protéine
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Growth Differentiation Factor 11 (GDF11) (AA 310-407) protein (GST tag)
GDF11 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Keep pH below 5.0.
- Buffer
- Supplied lyophilized with no additives.
- Agent conservateur
- Without preservative
- Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
- Stock
- RT/-20 °C
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- Antigène
- GDF11 (Growth Differentiation Factor 11 (GDF11))
- Autre désignation
- GDF11 (GDF11 Produits)
- Synonymes
- BMP-11 Protein, BMP11 Protein, Bmp11 Protein, GDF11 Protein, growth differentiation factor 11 Protein, GDF11 Protein, Gdf11 Protein, gdf11 Protein
- Sujet
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GDF-11 is a myostatin-homologous protein that acts as an inhibitor of nerve tissue growth. GDF-11 has been shown to suppress neurogenesis through a myostatin-like pathway, which involves arrest of progenitor cell-cycle in the G1 phase. Similarities between myostatin and GDF-11, which are 90 % identical in their amino acid sequence, suggests that the regulatory mechanisms responsible for maintaining proper tissue size during neural and muscular development might be the same.
Alternative Names: BMP-11 protein, GDF 11 protein, GDF-11 protein, GDF-11 protein, GDF-11, Growth/Differentiation Factor-11 protein, GDF11, GDF 11 - Poids moléculaire
- 25 kDa
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