CLCF1 Protéine

N° du produit ABIN935688

Détail du produit

Antigène: CLCF1 (Cardiotrophin-Like Cytokine Factor 1 (CLCF1))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Escherichia coli (E. coli)

Séquence: MLNRTGDPGP GPSIQKTYDL TRYLEHQLRS LAGTYLNYLG PPFNEPDFNP PRLGAETLPR ATVDLEVWRS LNDKLRLTQN YEAYSHLLCY LRGLNRQAAT AELRRSLAHF CTSLQGLLGS IAGVMAALGY PLPQPLPGTE PTWTPGPAHS DFLQKMDDFW LLKELQTWLW RSAKDFNRLK KKMQPPAAAV TLHLGAHGF

Attributs du produit: Purified recombinant Human NNT1 protein
Expression System: E.coli
Bioactivity: NT-1/BCSF-3 weakly supports chick E8 DRG neurite outgrowth at a concentration of 1.0 ng/mL.

Pureté: > 98 % pure

niveau d'endotoxine: < 0.1 ng per µg (1 EU/µg).

Information d'application

Indications d'application: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Supplied as a lyophilized powder.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.

Détail du antigène

Antigène: CLCF1 (Cardiotrophin-Like Cytokine Factor 1 (CLCF1))

Autre désignation: NNT1 (CLCF1 Produits)

Synonymes: clc Protein, nr6 Protein, bsf3 Protein, nnt1 Protein, ciss2 Protein, CLCF1 Protein, BSF-3 Protein, BSF3 Protein, CISS2 Protein, CLC Protein, NNT-1 Protein, NNT1 Protein, NR6 Protein, Bsf3 Protein, Clc Protein, cardiotrophin like cytokine factor 1 Protein, cardiotrophin-like cytokine factor 1 Protein, clcf1 Protein, CLCF1 Protein, Clcf1 Protein

Sujet: NNT-1/BCSF-3 is a neurotrophic factor with B-cell stimulating capabilities. Expressed in lymph nodes and spleen, NNT-1/BCSF-3 binds and activates glycoprotein 130 (gp130) and leukemia inhibitory factor receptor member beta (LIFR-beta) and induces tyrosine phosphorylation of these receptors. In vitro, it supports the survival of chick embryo motor and sympathetic neurons. In mice, NNT-1/BCSF-3 induces serum amyloid A, causes body weight loss and B cell hyperplasia associated with increased in serum IgG and IgM.
Alternative Names: NNT-1 protein, NNT-1 protein, Novel Neurtrophin-1/B-Cell Stimulating Factor-3 protein, Cardiotrophin-like cytokine protein, NNT 1, NNT 1 protein, NNT1, NNT-1

Poids moléculaire: 22.4 kDa

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response