NPX1 Protéine

N° du produit ABIN935691

Détail du produit

Antigène: NPX1 (Neuronal Pentraxin 1 (NPX1))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Escherichia coli (E. coli)

Séquence: ACYCRIPACI AGERRYGYCI YQGRLWAFCC

Attributs du produit: Purified recombinant Human NP1 protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract immature dendritic cells using a concentration of 1.0-10.0 ng/mL.

Pureté: > 98 % pure

niveau d'endotoxine: < 0.1 ng per µg (1 EU/µg).

Information d'application

Indications d'application: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Supplied as a lyophilized powder.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.

Détail du antigène

Antigène: NPX1 (Neuronal Pentraxin 1 (NPX1))

Autre désignation: NP1 (NPX1 Produits)

Synonymes: NP1 Protein, D11Bwg1004e Protein, Np1 Protein, np1 Protein, nptx1 Protein, neuronal pentraxin 1 Protein, neuronal pentraxin 1 L homeolog Protein, Nptx1 Protein, NPTX1 Protein, nptx1 Protein, nptx1.L Protein

Sujet: Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The a-defensins which include NP-1, NP-2 and NP-3, are distinguished from the beta-defensins by the pairing of their three disulfide bonds. In addition to antimicrobial activity, NP-1 exhibits chemotactic activity on dendritic cells. NP-1 is expressed as the C-terminal portion of an inactive precursor protein, which also contains a 19 amino acid N-terminal signal sequence and a 45 amino acid polypeptide. NP-1 contains a six-cysteine motif that forms three intra-molecular disulfide bonds.
Alternative Names: NP 1 protein, NP 1, Cryptdin protein, alpha Defensin-1 protein, Neutrophil Peptide-1 protein, HNP-1 protein, NP1, NP-1, NP-1 protein, NP-1 protein

Poids moléculaire: 3.4 kDa

Pathways: Carbohydrate Homeostasis, Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals, SARS-CoV-2 Protein Interactome