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PLA2G7 Protéine

Lp-PLA2 Origine: Humain Hôte: HEK-293T Cells Recombinant > 95 % pure Active
N° du produit ABIN935738
  • Antigène Voir toutes PLA2G7 (Lp-PLA2) Protéines
    PLA2G7 (Lp-PLA2) (Lipoprotein-Associated phospholipase A2 (Lp-PLA2))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Origine
    • 10
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Humain
    Source
    • 10
    • 6
    • 4
    • 1
    • 1
    HEK-293T Cells
    Séquence
    FDWQYINPVA HMKSSAWVNK IQVLMAAASF GQTKIPRGNG PYSVGCTDLM FDHTNKGTFL RLYYPSQDND RLDTLWIPNK EYFWGLSKFL GTHWLMGNIL RLLFGSMTTP ANWNSPLRPG EKYPLVVFSH GLGAFRTLYS AIGIDLASHG FIVAAVEHRD RSASATYYFK DQSAAEIGDK SWLYLRTLKQ EEETHIRNEQ VRQRAKECSQ ALSLILDIDH GKPVKNALDL KFDMEQLKDS IDREKIAVIG HSFGGATVIQ TLSEDQRFRC GIALDAWMFP LGDEVYSRIP QPLFFINSEY FQYPANIIKM KKCYSPDKER KMITIRGSVH QNFADFTFAT GKIIGHMLKL KGDIDSNVAI DLSNKASLAF LQKHLGLHKD FDQWDCLIEG DDENLIPGTN INTTNQHIML QNSSGIEKYN
    Attributs du produit
    Purified recombinant Human PAFAH protein
    Expression System: 293 cells
    Bioactivity: Measured by its ability to cleave a PAF analog in a chromogenic substrate linked assay. At a PAF-AH concentration of 10.0 µg/mL, 50 % cleavage was achieved at an incubation time of approximately 2 minutes.
    Pureté
    > 95 % pure
    niveau d'endotoxine
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product Lp-PLA2 Protéine
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Supplied as a lyophilized powder.
    Conseil sur la manipulation
    Avoid repeated freeze/thaw cycles.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • Antigène
    PLA2G7 (Lp-PLA2) (Lipoprotein-Associated phospholipase A2 (Lp-PLA2))
    Autre désignation
    PAFAH (Lp-PLA2 Produits)
    Sujet
    Platelet Activating Factor (PAF) is a biologically active phospholipid, which exerts primarily proinflammatory activities by specifically signaling through G-protein-coupled receptors on platelets, neutrophils, and monocytes. Platelet Activating Factor Acetylhydrolase (PAF-AH) is a secreted protein that mediates PAF activity by specifically catalyzing hydrolysis of the "sn2" ester bond, resulting in the conversion of PAF to the biologically inactive lyso-PAF. PAF-AH can also interact with LDL particles to induce the hydrolysis of LDL associated, oxidized phospholipids, generating lysophosphatidylcholine (lyso-PC) and other lysophospholipids.
    Alternative Names: PAF 2-acylhydrolase protein, PAF acetylhydrolase protein, LDL-associated phospholipase A2 protein, LDL-PLA2 protein, 2-acetyl-1-alkylglycerophosphocholine esterase protein, 1-alkyl-2-acetylglycerophosphocholine esterase protein
    Poids moléculaire
    47-55 kDa
    Pathways
    Peptide Hormone Metabolism
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