BNP
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 90 %
WB, SDS, Imm, PC
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20°C. Further dilutions should be made in appropriate buffered solutions.
Stock
4 °C
Moltzau, Aronsen, Meier, Skogestad, Ørstavik, Lothe, Sjaastad, Skomedal, Osnes, Levy, Qvigstad: "Different compartmentation of responses to brain natriuretic peptide and C-type natriuretic peptide in failing rat ventricle." dans: The Journal of pharmacology and experimental therapeutics, Vol. 350, Issue 3, pp. 681-90, (2014) (PubMed).
Lu, Fu, Chen, Lu, Yao, Shen, Gu: "Multiplex detection of B-type natriuretic peptide, cardiac troponin I and C-reactive protein with photonic suspension array." dans: PLoS ONE, Vol. 7, Issue 7, pp. e41448, (2012) (PubMed).
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Sujet
Natriuretic Peptide Precursor B acts as a cardiac hormone with a variety of biological actions including natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. It is thought to play a key role in cardiovascular homeostasis. Helps restore the body's salt and water balance. Improves heart function. Synonym:. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4.
Poids moléculaire
3464 Da, a single non-glycosylated polypeptide chain containing 32 amino acids.