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IL-13 Protéine

IL13 Origine: Souris Hôte: Escherichia coli (E. coli) > 97 % by SDS-PAGE and HPLC analyses. Active
N° du produit ABIN988037
  • Antigène Voir toutes IL-13 (IL13) Protéines
    IL-13 (IL13) (Interleukin 13 (IL13))
    Activité biologique
    Active
    Origine
    • 24
    • 13
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Souris
    Source
    • 28
    • 15
    • 8
    • 7
    • 2
    • 1
    Escherichia coli (E. coli)
    Séquence
    MPVPRSVSLP LTLKELIEEL SNITQDQTPL CNGSMVWSVD LAAGGFCVAL DSLTNISNCN AIYRTQRILH GLCNRKAPTT VSSLPDTKIE VAHFITKLLS YTKQLFRHGP
    Attributs du produit
    The ED50 as determined by the dose-dependent proliferation of TF-1 cells was < 4.0 ng/ml, corresponding to a specific activity of > 2.5 x 105 units/mg.
    Pureté
    > 97 % by SDS-PAGE and HPLC analyses.
    niveau d'endotoxine
    Level Less than 1EU/µg of rMuIL-13 as determined by LAL method
    Top Product
    Discover our top product IL13 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at
    Stock
    4 °C
  • Antigène
    IL-13 (IL13) (Interleukin 13 (IL13))
    Autre désignation
    Interleukin-13 (IL-13) (IL13 Produits)
    Synonymes
    IL13 Protein, IL-13 Protein, P600 Protein, Il-13 Protein, L13 Protein, interleukin 13 Protein, IL13 Protein, Il13 Protein
    Sujet
    IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1beta, TNF-alpha, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human and mouse IL-13 is cross-species reactive. Synonym:. Formulation: Lyophilized from a 0.2µm filtered solution in PBS, pH 7.4.
    Poids moléculaire
    Approximately 12.3 kDa, a single non-glycosylated polypeptide chain containing 111 amino acids.
    Pathways
    Signalistation JAK/STAT, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
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