CCL22 Protéine

N° du produit ABIN988125

Détail du produit

Antigène: CCL22 (Chemokine (C-C Motif) Ligand 22 (CCL22))

Activité biologique: Active

Origine: Humain

Source: Escherichia coli (E. coli)

Séquence: GPYGANMEDS VCCRDYVRYR LPLRVVKHFY WTSDSCPRPG VVLLTFRDKE ICADPRVPWV KMILNKLS

Attributs du produit: Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human T-lymphocytes is less than 100 ng/ml, corresponding to a specific activity of >, 1.0 × 104 IU/mg.

Pureté: > 97 % by SDS-PAGE and HPLC analyses.

niveau d'endotoxine: Level Less than 1EU/µg of rHuMDC/CCL22 as determined by LAL method

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.

Stock: 4 °C

Détail du antigène

Antigène: CCL22 (Chemokine (C-C Motif) Ligand 22 (CCL22))

Autre désignation: Macrophage-Derived Chemokine/CCL22 (CCL22 Produits)

Synonymes: ABCD-1 Protein, DC/B-CK Protein, MDC Protein, SCYA22 Protein, STCP-1 Protein, DCBCK Protein, Scya22 Protein, Mdc Protein, CCL22 Protein, C-C motif chemokine ligand 22 Protein, chemokine (C-C motif) ligand 22 Protein, CCL22 Protein, Ccl22 Protein

Sujet: MDC is a CC chemokine that is produced in B cells, macrophages, monocyte-derived dendritic cells, activated NK cells and CD4 T cells. It signals through the CCR4 receptor. MDC chemoattracts monocytes, dendritic cells and NK cells and exerts HIV suppressive activity. Synonym: Macrophage-Derived Chemokine/CCL22 (69a.a.), Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH7.4, 500mM NaCl.

Poids moléculaire: 8.1 kDa, a single, non-glycosylated polypeptide chain containing 69 amino acids.