PTH Protein (AA 1-34)

N° du produit ABIN988194

Détail du produit

Antigène: PTH (Parathyroid Hormone (PTH))

Activité biologique: Active

Attributs du protein: AA 1-34

Origine: Humain

Source: Escherichia coli (E. coli)

Séquence: SVSEIQLMHN LGKHLNSMER VEWLRKKLQD VHN

Attributs du produit: Fully biologically active when compared to standard. The specific activity is determined by UMR106 cell/cAMP method, corresponding to a specific activity of >, 1.0 × 104 IU/mg.

Pureté: > 97 % by SDS-PAGE and HPLC analyses.

niveau d'endotoxine: Level Less than 1EU/µg of rHuPTH1-34 as determined by LAL method

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.

Stock: 4 °C

Détail du antigène

Antigène: PTH (Parathyroid Hormone (PTH))

Autre désignation: Parathyroid Hormone( PTH) (PTH Produits)

Synonymes: PTH1 Protein, Pthp Protein, PTH-(1-84) Protein, Pth1 Protein, Pthr1 Protein, PTH Protein, parathyroid hormone Protein, parathyroid hormone S homeolog Protein, PTH Protein, Pth Protein, pth.S Protein

Classe de substances: Hormone

Sujet: Polypeptide hormones secreted by the parathyroid glands, which promote release of calcium from bone to extracellular fluid by activating osteoblasts and inhibiting osteoclasts, indirectly promote increased intestinal absorption of calcium, and promote renal tubular reabsorption of calcium and increased renal excretion of phosphates. It is a major regulator of bone metabolism. Secretion of parathyroid hormone increases when the level of calcium in the extracellular fluid is low. Its action is opposed by calcitonin. Synonym: Parathyroid Hormone 1-34 ( PTH 1-34 ), Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.0, containing 4% mannitol.

Poids moléculaire: 4117.8 Da, a single non-glycosylated polypeptide chain containing 34 amino acids.

Pathways: cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process