PSMD2 Produits
(Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 2 (PSMD2))
Catégories
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. In addition to participation in proteasome function, this subunit may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor. A pseudogene has been identified on chromosome 1. [provided by RefSeq, Jul 2008].
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Catégories PSMD2 en vedette
PSMD2 Anticorps
High quality antibodies with extensive validation data.
PSMD2 Kits ELISA
Reliable ELISA kits for a wide range of species.
PSMD2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PSMD2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (8)
N° du produit
ABIN7439738
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (6)
N° du produit
ABIN3015813
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Dog, Human, Monkey, Mouse, Rat
Application
WB, IF, IHC, IHC (p)
Validations
- (11)
N° du produit
ABIN1500479
Quantité
100 μL
Fiche technique
Fiche technique
PSMD2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN5648250
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Chicken
Analytical Method
Validations
N° du produit
ABIN1773469
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Sheep
Analytical Method
Validations
N° du produit
ABIN1774693
Quantité
96 tests
Fiche technique
Fiche technique
PSMD2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1316633
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7405741
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3094827
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits PSMD2
: "Acute ethanol exposure reduces serotonin receptor 1A internalization by increasing ubiquitination and degradation of β-arrestin2." dans: The Journal of biological chemistry, Vol. 294, Issue 38, pp. 14068-14080, (2019) (PubMed).: "The transition zone protein Rpgrip1l regulates proteasomal activity at the primary cilium." dans: The Journal of cell biology, Vol. 210, Issue 1, pp. 115-33, (2015) (PubMed).
: "Angiopoietin-2 secretion by endothelial cell exosomes: regulation by the phosphatidylinositol 3-kinase (PI3K)/Akt/endothelial nitric oxide synthase (eNOS) and syndecan-4/syntenin pathways." dans: The Journal of biological chemistry, Vol. 289, Issue 1, pp. 510-9, (2014) (PubMed).
: "Impairment of proteostasis network in Down syndrome prior to the development of Alzheimer's disease neuropathology: redox proteomics analysis of human brain." dans: Biochimica et biophysica acta, Vol. 1832, Issue 8, pp. 1249-59, (2013) (PubMed).
: "NAK is recruited to the TNFR1 complex in a TNFalpha-dependent manner and mediates the production of RANTES: identification of endogenous TNFR-interacting proteins by a proteomic approach." dans: The Journal of biological chemistry, Vol. 279, Issue 51, pp. 53266-71, (2004) (PubMed).
Synonymes et noms alternatifs relatifs à PSMD2
26S proteasome non-ATPase regulatory subunit 2 (psmD2), 26S proteasome regulatory subunit S2 (NAEGRDRAFT_83014), 26S proteasome regulatory subunit S2 (DICPUDRAFT_55026), proteasome 26S subunit, non-ATPase 2 (psmd2), proteasome 26S subunit, non-ATPase 2 L homeolog (psmd2.L), proteasome 26S subunit, non-ATPase 2 S homeolog (psmd2.S), proteasome 26S subunit, non-ATPase 2 (PSMD2), proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 (psmd2), proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 (Psmd2), proteasome 26S subunit, non-ATPase 2 (Psmd2), 9430095H01Rik, AA407121, DDBDRAFT_0192101, DDBDRAFT_0232978, DDB_0192101, DDB_0232978, MGC83233, MGC97650, P97, psmd2, PSMD2, RPN1, S2, TEG-190, Tex190, TRAP2, zgc:65921Protein level used designations for PSMD2
- 26S proteasome regulatory subunit S2
- 26S proteasome non-ATPase regulatory subunit 2
- 26s proteasome regulatory subunit S2-like protein
- proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
- proteasome 26S non-ATPase subunit 2
- 55.11 protein
- TNFR-associated protein 2
- protein 55.11
- tumor necrosis factor type 1 receptor-associated protein 2
- 26S proteasome regulatory subunit RPN1
- 26S proteasome subunit p97
- testis expressed gene 190
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