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PSMD4/ASF Produits

(Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4))

Catégories

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. Pseudogenes have been identified on chromosomes 10 and 21. [provided by RefSeq, Jul 2008].

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Catégories PSMD4/ASF en vedette

PSMD4/ASF Anticorps

High quality antibodies with extensive validation data.

PSMD4/ASF Kits ELISA

Reliable ELISA kits for a wide range of species.

PSMD4/ASF Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PSMD4/ASF recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IF, IP
Validations
  • (5)
N° du produit ABIN3021330
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
N° du produit ABIN7142212
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (3)
N° du produit ABIN519398
Quantité 100 μg
Fiche technique Fiche technique

PSMD4/ASF recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969691
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6975602
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Pig
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN778103
Quantité 96 tests
Fiche technique Fiche technique

PSMD4/ASF recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1316639
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1316641
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN1343997
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits PSMD4/ASF

Kuzina, Kudriaeva, Smirnov, Dubina, Gabibov, Belogurov: "Glatiramer acetate and nanny proteins restrict access of the multiple sclerosis autoantigen myelin basic protein to the 26S proteasome." dans: BioMed research international, Vol. 2014, pp. 926394, (2014) (PubMed).

Elangovan, Oh, Sukumaran, Wójcik, Yoo: "Functional differences between two major ubiquitin receptors in the proteasome; S5a and hRpn13." dans: Biochemical and biophysical research communications, Vol. 396, Issue 2, pp. 425-8, (2010) (PubMed).

Safadi, Shaw: "Differential interaction of the E3 ligase parkin with the proteasomal subunit S5a and the endocytic protein Eps15." dans: The Journal of biological chemistry, Vol. 285, Issue 2, pp. 1424-34, (2010) (PubMed).

Zhang, Wang, Ehlinger, Randles, Lary, Kang, Haririnia, Storaska, Cole, Fushman, Walters: "Structure of the s5a:k48-linked diubiquitin complex and its interactions with rpn13." dans: Molecular cell, Vol. 35, Issue 3, pp. 280-90, (2009) (PubMed).

Kim, Kim, Uchiki, Gygi, Goldberg: "S5a promotes protein degradation by blocking synthesis of nondegradable forked ubiquitin chains." dans: The EMBO journal, Vol. 28, Issue 13, pp. 1867-77, (2009) (PubMed).

Gaurnier-Hausser, Tuszynski: "The immunomodulatory role of angiocidin, a novel angiogenesis inhibitor." dans: Current pharmaceutical design, Vol. 15, Issue 17, pp. 1937-48, (2009) (PubMed).

Ghi, Di Brisco, Dallorto, Osella, Orsetti: "Age-related modifications of egr1 expression and ubiquitin-proteasome components in pet dog hippocampus." dans: Mechanisms of ageing and development, Vol. 130, Issue 5, pp. 320-7, (2009) (PubMed).

Walters, Kleijnen, Goh, Wagner, Howley: "Structural studies of the interaction between ubiquitin family proteins and proteasome subunit S5a." dans: Biochemistry, Vol. 41, Issue 6, pp. 1767-77, (2002) (PubMed).

Tanahashi, Murakami, Minami, Shimbara, Hendil, Tanaka: "Hybrid proteasomes. Induction by interferon-gamma and contribution to ATP-dependent proteolysis." dans: The Journal of biological chemistry, Vol. 275, Issue 19, pp. 14336-45, (2000) (PubMed).

Kawahara, Kasahara, Nishiyama, Ohsumi, Goto, Kishimoto, Saeki, Yokosawa, Shimbara, Murata, Chiba, Suzuki, Tanaka: "Developmentally regulated, alternative splicing of the Rpn10 gene generates multiple forms of 26S proteasomes." dans: The EMBO journal, Vol. 19, Issue 15, pp. 4144-53, (2000) (PubMed).

Synonymes et noms alternatifs relatifs à PSMD4/ASF

proteasome 26S subunit, non-ATPase 4 (psmd4), proteasome 26S subunit, non-ATPase 4 (PSMD4), 26S proteasome non-ATPase regulatory subunit 4 (LOC100194679), 26S proteasome non-ATPase regulatory subunit 4 (psmD4), 26S proteasome non-ATPase regulatory subunit 4 (LOC100283637), 26s proteasome non-atpase regulatory subunit 4 (26s proteasomeregulatory subunit s5a) (Smp_000740.1), proteasome 26S subunit, non-ATPase 4 L homeolog (psmd4.L), proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 (Psmd4), proteasome 26S subunit, non-ATPase 4 (Psmd4), proteasome 26S subunit, non-ATPase 4b (psmd4b), AF, af-1, AF-1, Af1, angiocidin, ASF, DDBDRAFT_0202512, DDBDRAFT_0232981, DDB_0202512, DDB_0232981, im:6912672, mcb1, MCB1, Mcb1, PSMD4, psmd4, pub-r5, pUB-R5, rpn10, Rpn10, S5A, wu:fc68c04, xrpn10c, zgc:110247

Protein level used designations for PSMD4/ASF

  • proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
  • anti-secretory factor
  • 26S proteasome non-ATPase regulatory subunit 4
  • 26S proteasome subunit
  • 26S proteasome regulatory subunit S5A
  • type A von Willebrand factor domain-containing protein
  • ubiquitin interacting motif domain-containing protein
  • proteasome 26S subunit, non-ATPase, 4
  • RPN10 homolog
  • S5a/antisecretory factor protein
  • angiocidin
  • antisecretory factor 1
  • multiubiquitin chain-binding protein
  • proteasome 26S subunit non-ATPase 4
  • 26S proteasome regulatory subunit RPN10
  • proteasome 26S non-ATPase subunit 4
  • anti secretory factor 1
  • multiubiquitin-chain-binding protein
  • antisecretory factor
  • psmd4l
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