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PSMF1 Produits

(Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31) (PSMF1))

Catégories

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified for this gene. [provided by RefSeq, Jul 2008].

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Catégories PSMF1 en vedette

PSMF1 Anticorps

High quality antibodies with extensive validation data.

PSMF1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PSMF1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF
Validations
  • (5)
N° du produit ABIN184933
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
N° du produit ABIN7164936
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (3)
N° du produit ABIN1500490
Quantité 100 μL
Fiche technique Fiche technique

PSMF1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6229191
Quantité 96 tests
Fiche technique Fiche technique

PSMF1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7124622
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN2131394
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN5711688
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits PSMF1

Li, Thompson, Kumar, DeMartino: "Molecular and cellular roles of PI31 (PSMF1) protein in regulation of proteasome function." dans: The Journal of biological chemistry, Vol. 289, Issue 25, pp. 17392-405, (2014) (PubMed).

Sadaka, Marloie-Provost, Soumelis, Benaroch: "Developmental regulation of MHC II expression and transport in human plasmacytoid-derived dendritic cells." dans: Blood, Vol. 113, Issue 10, pp. 2127-35, (2009) (PubMed).

McCutchen-Maloney, Matsuda, Shimbara, Binns, Tanaka, Slaughter, DeMartino: "cDNA cloning, expression, and functional characterization of PI31, a proline-rich inhibitor of the proteasome." dans: The Journal of biological chemistry, Vol. 275, Issue 24, pp. 18557-65, (2000) (PubMed).

Synonymes et noms alternatifs relatifs à PSMF1

proteasome inhibitor subunit 1 (PSMF1), proteasome inhibitor subunit 1 (Psmf1), proteasome (prosome, macropain) inhibitor subunit 1 (Psmf1), proteasome inhibitor subunit 1 (psmf1), AW048666, BC012260, PI31, zgc:92785

Protein level used designations for PSMF1

  • hPI31
  • proteasome inhibitor PI31 subunit
  • proteasome inhibitor hP131 subunit
  • proteasome inhibitor subunit 1
  • proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
  • proteasome (prosome, macropain) inhibitor subunit 1
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